Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions

S. Paracchini; L. Stuppia; V. Gatta; G. Palka; E. Moro; C. Foresta; L. Mengua; R. Oliva; J. L. Ballesca; J. A.M. Kremer; R. J.T. Van Golde; J. H.A.M. Tuerlings; T. Hargreave; A. Ross; H. Cooke; K. Huellen; P. H. Vogt; C. Tyler-Smith

doi:10.1007/BF03343792

Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions

S. Paracchini, L. Stuppia, V. Gatta, G. Palka, E. Moro, C. Foresta, L. Mengua, R. Oliva, J. L. Ballesca, J. A.M. Kremer, R. J.T. Van Golde, J. H.A.M. Tuerlings, T. Hargreave, A. Ross, H. Cooke, K. Huellen, P. H. Vogt, C. Tyler-Smith^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

We have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplogroup frequencies were compared between 3 microdeletion classes and the non-deleted infertile males. Deletions arise on many different haplotypic backgrounds. No statistically significant differences in frequency were seen, although the small number of AZFa deletions lay predominantly on one branch of the Y haplotype tree. (C)2000, Editrice Kurtice.

Original language	English
Pages (from-to)	671-676
Number of pages	6
Journal	Journal of Endocrinological Investigation
Volume	23
Issue number	10
DOIs	https://doi.org/10.1007/BF03343792
Publication status	Published - 1 Jan 2000

Keywords

Association study
Haplotype
Infertility
Microdeletion
Y chromosome

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/BF03343792

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Paracchini, S., Stuppia, L., Gatta, V., Palka, G., Moro, E., Foresta, C., Mengua, L., Oliva, R., Ballesca, J. L., Kremer, J. A. M., Van Golde, R. J. T., Tuerlings, J. H. A. M., Hargreave, T., Ross, A., Cooke, H., Huellen, K., Vogt, P. H., & Tyler-Smith, C. (2000). Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions. Journal of Endocrinological Investigation, 23(10), 671-676. https://doi.org/10.1007/BF03343792

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title = "Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions",

abstract = "We have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplogroup frequencies were compared between 3 microdeletion classes and the non-deleted infertile males. Deletions arise on many different haplotypic backgrounds. No statistically significant differences in frequency were seen, although the small number of AZFa deletions lay predominantly on one branch of the Y haplotype tree. (C)2000, Editrice Kurtice.",

keywords = "Association study, Haplotype, Infertility, Microdeletion, Y chromosome",

author = "S. Paracchini and L. Stuppia and V. Gatta and G. Palka and E. Moro and C. Foresta and L. Mengua and R. Oliva and Ballesca, {J. L.} and Kremer, {J. A.M.} and {Van Golde}, {R. J.T.} and Tuerlings, {J. H.A.M.} and T. Hargreave and A. Ross and H. Cooke and K. Huellen and Vogt, {P. H.} and C. Tyler-Smith",

year = "2000",

month = jan,

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doi = "10.1007/BF03343792",

language = "English",

volume = "23",

pages = "671--676",

journal = "Journal of Endocrinological Investigation",

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Paracchini, S, Stuppia, L, Gatta, V, Palka, G, Moro, E, Foresta, C, Mengua, L, Oliva, R, Ballesca, JL, Kremer, JAM, Van Golde, RJT, Tuerlings, JHAM, Hargreave, T, Ross, A, Cooke, H, Huellen, K, Vogt, PH & Tyler-Smith, C 2000, 'Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions', Journal of Endocrinological Investigation, vol. 23, no. 10, pp. 671-676. https://doi.org/10.1007/BF03343792

TY - JOUR

T1 - Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions

AU - Paracchini, S.

AU - Stuppia, L.

AU - Gatta, V.

AU - Palka, G.

AU - Moro, E.

AU - Foresta, C.

AU - Mengua, L.

AU - Oliva, R.

AU - Ballesca, J. L.

AU - Kremer, J. A.M.

AU - Van Golde, R. J.T.

AU - Tuerlings, J. H.A.M.

AU - Hargreave, T.

AU - Ross, A.

AU - Cooke, H.

AU - Huellen, K.

AU - Vogt, P. H.

AU - Tyler-Smith, C.

PY - 2000/1/1

Y1 - 2000/1/1

N2 - We have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplogroup frequencies were compared between 3 microdeletion classes and the non-deleted infertile males. Deletions arise on many different haplotypic backgrounds. No statistically significant differences in frequency were seen, although the small number of AZFa deletions lay predominantly on one branch of the Y haplotype tree. (C)2000, Editrice Kurtice.

AB - We have determined Y-chromosomal DNA haplotypes in 73 infertile European males carrying Y microdeletions and compared them with the haplotypes of 299 infertile males lacking microdeletions. Chromosomes were typed with a set of 11 binary Y markers, which identified 8 haplogroups in the sample. Haplogroup frequencies were compared between 3 microdeletion classes and the non-deleted infertile males. Deletions arise on many different haplotypic backgrounds. No statistically significant differences in frequency were seen, although the small number of AZFa deletions lay predominantly on one branch of the Y haplotype tree. (C)2000, Editrice Kurtice.

KW - Association study

KW - Haplotype

KW - Infertility

KW - Microdeletion

KW - Y chromosome

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U2 - 10.1007/BF03343792

DO - 10.1007/BF03343792

M3 - Article

C2 - 11097432

AN - SCOPUS:0033692865

SN - 0391-4097

VL - 23

SP - 671

EP - 676

JO - Journal of Endocrinological Investigation

JF - Journal of Endocrinological Investigation

IS - 10

ER -

Y-chromosomal DNA haplotypes in infertile European males carrying Y-microdeletions

Abstract

Keywords

UN SDGs

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