Projects per year
Abstract
In a prototypical response to an acute viral infection it would be expected that the adaptive immune response would eliminate all virally infected cells within a few weeks of infection. However many (non-retrovirus) RNA viruses can establish “within host” persistent infections that occasionally lead to chronic or reactivated disease. Despite the importance of “within host” persistent RNA virus infections, much has still to be learnt about the molecular mechanisms by which RNA viruses establish persistent infections, why innate and adaptive immune responses fail to rapidly clear these infections, and the epidemiological and potential disease consequences of such infections.
Original language | English |
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Pages (from-to) | 35-42 |
Number of pages | 8 |
Journal | Current Opinion in Virology |
Volume | 23 |
Early online date | 17 Mar 2017 |
DOIs | |
Publication status | Published - Apr 2017 |
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Dive into the research topics of 'Within host RNA virus persistence: mechanisms and consequences'. Together they form a unique fingerprint.Projects
- 1 Finished
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Prof Randall Wellcome Trust: The interaction of paramyxoviruses with the interferon system
Randall, R. E. (PI)
1/04/14 → 31/03/20
Project: Standard