Well-defined, air-stable (NHC)Pd(Allyl)Cl (NHC = N-heterocyclic carbene) catalysts for the arylation of ketones

M S Viciu, R F Germaneau, Steven Patrick Nolan

Research output: Contribution to journalArticlepeer-review

244 Citations (Scopus)

Abstract

[GRAPHICS]

A number of palladium-N-heterocyclic carbene (NHC) complexes were found to be active catalysts for the arylation of ketones. A large number of substrates, both aryl halides and ketones, are compatible with the reaction conditions. The ketone arylation reactions are achieved with low catalyst loading in short reaction times using aryl chlorides and triflates; as reactive partners.

Original languageEnglish
Pages (from-to)4053-4056
Number of pages4
JournalOrganic Letters
Volume4
Issue number23
DOIs
Publication statusPublished - 14 Nov 2002

Keywords

  • CROSS-COUPLING REACTIONS
  • ALPHA-ARYLATION
  • ARYL CHLORIDES
  • COMPLEXES
  • CHEMISTRY
  • HALIDES
  • SYSTEM
  • ACIDS

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