Wavelength-orthogonal photolysis of neurotransmitters in vitro

Megan N. Stanton-Humphreys; Ruth D. T. Taylor; Craig McDougall; Mike L. Hart; C. Tom A. Brown; Nigel J. Emptage; Stuart J. Conway

doi:10.1039/c1cc15135e

Wavelength-orthogonal photolysis of neurotransmitters in vitro

Megan N. Stanton-Humphreys
, Ruth D. T. Taylor
, Craig McDougall
, Mike L. Hart
, C. Tom A. Brown
, Nigel J. Emptage
, Stuart J. Conway

Research output: Contribution to journal › Article › peer-review

Abstract

Irradiation of a mixture of 4-methoxyphenacyl-caged (S)-glutamate and 4,5-dimethoxy-2-nitrobenzyl-caged gamma-amino butyric acid (GABA) on neurons, at similar to 260 nm, evokes selective photorelease of (S)-glutamate (Glu) whereas photolysis at 405 nm causes selective photorelease of GABA.

Original language	English
Pages (from-to)	657-659
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	5
DOIs	https://doi.org/10.1039/c1cc15135e
Publication status	Published - 2012

Access to Document

10.1039/c1cc15135e

Handle.net

Persistent link to portal record

Cite this

@article{fd22da314e8a4ebb9861d07186f828b7,

title = "Wavelength-orthogonal photolysis of neurotransmitters in vitro",

abstract = "Irradiation of a mixture of 4-methoxyphenacyl-caged (S)-glutamate and 4,5-dimethoxy-2-nitrobenzyl-caged gamma-amino butyric acid (GABA) on neurons, at similar to 260 nm, evokes selective photorelease of (S)-glutamate (Glu) whereas photolysis at 405 nm causes selective photorelease of GABA.",

author = "Stanton-Humphreys, \{Megan N.\} and Taylor, \{Ruth D. T.\} and Craig McDougall and Hart, \{Mike L.\} and Brown, \{C. Tom A.\} and Emptage, \{Nigel J.\} and Conway, \{Stuart J.\}",

year = "2012",

doi = "10.1039/c1cc15135e",

language = "English",

volume = "48",

pages = "657--659",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "5",

}

TY - JOUR

T1 - Wavelength-orthogonal photolysis of neurotransmitters in vitro

AU - Stanton-Humphreys, Megan N.

AU - Taylor, Ruth D. T.

AU - McDougall, Craig

AU - Hart, Mike L.

AU - Brown, C. Tom A.

AU - Emptage, Nigel J.

AU - Conway, Stuart J.

PY - 2012

Y1 - 2012

N2 - Irradiation of a mixture of 4-methoxyphenacyl-caged (S)-glutamate and 4,5-dimethoxy-2-nitrobenzyl-caged gamma-amino butyric acid (GABA) on neurons, at similar to 260 nm, evokes selective photorelease of (S)-glutamate (Glu) whereas photolysis at 405 nm causes selective photorelease of GABA.

AB - Irradiation of a mixture of 4-methoxyphenacyl-caged (S)-glutamate and 4,5-dimethoxy-2-nitrobenzyl-caged gamma-amino butyric acid (GABA) on neurons, at similar to 260 nm, evokes selective photorelease of (S)-glutamate (Glu) whereas photolysis at 405 nm causes selective photorelease of GABA.

U2 - 10.1039/c1cc15135e

DO - 10.1039/c1cc15135e

M3 - Article

SN - 1359-7345

VL - 48

SP - 657

EP - 659

JO - Chemical Communications

JF - Chemical Communications

IS - 5

ER -

Wavelength-orthogonal photolysis of neurotransmitters in vitro

Abstract

Access to Document

Handle.net

Fingerprint

Cite this