Voltage-dependent block by histrionicotoxin of the acetylcholine-induced current in an insect motoneurone cell body

D. B. Satelle; J. A. David

doi:10.1016/0304-3940(83)90125-8

Voltage-dependent block by histrionicotoxin of the acetylcholine-induced current in an insect motoneurone cell body

D. B. Satelle^*
, J. A. David

^*Corresponding author for this work

School of Biology

Research output: Contribution to journal › Article › peer-review

Abstract

Acetylcholine (ACh)-induced currents were recorded from the voltage-clamped cell body of the fast coxal depressor motoneurone of the cockroach Periplaneta americana, at membrane potentials in the range -120 mV to -60 mV. In the presence of histrionicotoxin (HTX) (1.0 × 10^-6 M), ACh currents were blocked. The blocking action of HTX was voltage-dependent, being more negative membrane potentials.

Original language	English
Pages (from-to)	37-41
Number of pages	5
Journal	Neuroscience Letters
Volume	43
Issue number	1
DOIs	https://doi.org/10.1016/0304-3940(83)90125-8
Publication status	Published - 23 Dec 1983

Keywords

acetylcholine-induced current
histrionicotoxin
insect motoneurone
voltage-dependent antagonism

Access to Document

10.1016/0304-3940(83)90125-8

Handle.net

Persistent link to portal record

Cite this

@article{5113e538989a457792827108b55ffe71,

title = "Voltage-dependent block by histrionicotoxin of the acetylcholine-induced current in an insect motoneurone cell body",

abstract = "Acetylcholine (ACh)-induced currents were recorded from the voltage-clamped cell body of the fast coxal depressor motoneurone of the cockroach Periplaneta americana, at membrane potentials in the range -120 mV to -60 mV. In the presence of histrionicotoxin (HTX) (1.0 × 10-6 M), ACh currents were blocked. The blocking action of HTX was voltage-dependent, being more negative membrane potentials.",

keywords = "acetylcholine-induced current, histrionicotoxin, insect motoneurone, voltage-dependent antagonism",

author = "Satelle, \{D. B.\} and David, \{J. A.\}",

year = "1983",

month = dec,

day = "23",

doi = "10.1016/0304-3940(83)90125-8",

language = "English",

volume = "43",

pages = "37--41",

journal = "Neuroscience Letters",

issn = "0304-3940",

publisher = "Elsevier Ireland Ltd",

number = "1",

}

TY - JOUR

T1 - Voltage-dependent block by histrionicotoxin of the acetylcholine-induced current in an insect motoneurone cell body

AU - Satelle, D. B.

AU - David, J. A.

PY - 1983/12/23

Y1 - 1983/12/23

N2 - Acetylcholine (ACh)-induced currents were recorded from the voltage-clamped cell body of the fast coxal depressor motoneurone of the cockroach Periplaneta americana, at membrane potentials in the range -120 mV to -60 mV. In the presence of histrionicotoxin (HTX) (1.0 × 10-6 M), ACh currents were blocked. The blocking action of HTX was voltage-dependent, being more negative membrane potentials.

AB - Acetylcholine (ACh)-induced currents were recorded from the voltage-clamped cell body of the fast coxal depressor motoneurone of the cockroach Periplaneta americana, at membrane potentials in the range -120 mV to -60 mV. In the presence of histrionicotoxin (HTX) (1.0 × 10-6 M), ACh currents were blocked. The blocking action of HTX was voltage-dependent, being more negative membrane potentials.

KW - acetylcholine-induced current

KW - histrionicotoxin

KW - insect motoneurone

KW - voltage-dependent antagonism

UR - https://www.scopus.com/pages/publications/0021072743

U2 - 10.1016/0304-3940(83)90125-8

DO - 10.1016/0304-3940(83)90125-8

M3 - Article

AN - SCOPUS:0021072743

SN - 0304-3940

VL - 43

SP - 37

EP - 41

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 1

ER -

Voltage-dependent block by histrionicotoxin of the acetylcholine-induced current in an insect motoneurone cell body

Abstract

Keywords

Access to Document

Handle.net

Other files and links

Fingerprint

Cite this