Villoglandular adenocarcinoma of the cervix: clarity is needed on the histological definition for this difficult diagnosis

R Macdonald, J Kirwan, K Hayat, Charles Simon Herrington, H Shawki

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

Background. Villoglandular adenocarcinoma (VGA) of the cervix is reported as a variant of a cervical adenocarcinoma with a good prognosis.

Cases. We present two cases histologically reported as a villoglandular adenocarcinoma of the cervix that have recurred and progressed rapidly since initial treatment. External histopathological review suggested both had a prominent villoglandular pattern but with an associated underlying well-differentiated adenocarcinoma.

Conclusion. The diagnosis of VGA is difficult. Current literature is not entirely consistent in the presented definition, and further clarity is needed. Because of the rarity of VGA and the difficulty but importance of the diagnosis, we Would feel that a central review of all cases of VGA is warranted. This would assist in diagnosis and also in obtaining accurate follow-tip data. (c) 2005 Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)192-194
Number of pages3
JournalGynecologic Oncology
Volume100
DOIs
Publication statusPublished - Jan 2006

Keywords

  • cervix
  • villoglandular adenocarcinoma
  • PAPILLARY ADENOCARCINOMA
  • UTERINE CERVIX

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