Vertical graphene nanoflakes for the immobilization, electrocatalytic oxidation and quantitative detection of DNA

Naigui Shang, Ajay Kumar, Nijuan Sun, Surbhi Sharma, Pagona Papakonstantinou, Meixian Li, Ross A. Blackley, Wuzong Zhou, Lisa S. Karlsson, S. Ravi P. Silva

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Vertical graphene nanoflake integrated films having a high density of edge planes have been used as an electrochemical platform to systematically investigate the immobilization, electrochemical oxidation kinetics and direct quantitative determination of native DNA. Consistently, both transmission electron microscopy and atomic force microscopy observations demonstrate the presence of a self-assembled monolayer of native DNA, immobilized on the graphene nanoflakes. Graphene shows excellent electrocatalytic activity for the electrooxidation of double stranded DNA, better than carbon nanotubes and glassy carbon, due to the abundance of electrocatalytic graphene edges present not only at the top but also along the sides of each graphene nanoflake. (C) 2012 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)140-143
Number of pages4
JournalElectrochemistry Communications
Volume25
DOIs
Publication statusPublished - Nov 2012

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