Versatile relay and cooperative palladium(0) N-heterocyclic carbene/copper(I) N-heterocyclic carbene catalysis for the synthesis of tri- and tetrasubstituted alkenes

Mathieu Lesieur, Yannick Daniel Bidal, Faima Lazreg, Fady Nahra, Catherine S.J. Cazin

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)
4 Downloads (Pure)

Abstract

Two new and efficient dual catalytic procedures for the synthesis of tri- and tetra-substituted alkenes using aryl bromides and chlorides are reported. The formation of these vinyl arenes occurs independently in a one-pot relay and a one-pot cooperative procedure using well-defined Pd-NHC and Cu-NHC complexes. Mechanistic studies were performed to elucidate the key role of the solvent in each procedure as well as the formation of the key intermediate, [Cu(alkenylboron)(NHC)], allowing the transmetallation with the Pd-NHC co-catalyst in the cooperative catalysis.
Original languageEnglish
Pages (from-to)2108–2112
JournalChemCatChem
Volume7
Issue number14
Early online date26 Jun 2015
DOIs
Publication statusPublished - 13 Jul 2015

Keywords

  • Alkenes
  • Copper
  • Palladium
  • N-heterocyclic
  • Carbene
  • Dual catalysis

Fingerprint

Dive into the research topics of 'Versatile relay and cooperative palladium(0) N-heterocyclic carbene/copper(I) N-heterocyclic carbene catalysis for the synthesis of tri- and tetrasubstituted alkenes'. Together they form a unique fingerprint.

Cite this