Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer

Bernard Pope; Gahee Park; Edmund  Lau; Jelena Belic; Radoslaw Lach; Anne George; Patrick McCoy; Anne Nguyen; Corrina Grima; Bethany Campbell; Chol-hee Jung; Emma-Jane Ditter; Hui Zhao; David Wedge; Daniel Brewer; Andy Lynch; Harveer Dev; Vincent Gnanpragasam; Nitzan Rosenfeld; Christopher Hovens; Niall Corcoran; Charlie Massie; CR-UK/Prostate Cancer UK, ICGC, The PPCG

doi:10.1016/j.eururo.2024.01.002

Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer

Bernard Pope^*
, Gahee Park
, Edmund Lau
, Jelena Belic
, Radoslaw Lach
, Anne George
, Patrick McCoy
, Anne Nguyen
, Corrina Grima
, Bethany Campbell
, Chol-hee Jung
, Emma-Jane Ditter
, Hui Zhao
, David Wedge
, Daniel Brewer
, Andy Lynch
, Harveer Dev
, Vincent Gnanpragasam
, Nitzan Rosenfeld
, Christopher Hovens

Niall Corcoran, Charlie Massie, CR-UK/Prostate Cancer UK, ICGC, The PPCG

^*Corresponding author for this work

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	407-410
Number of pages	4
Journal	European Urology
Volume	85
Issue number	4
Early online date	19 Feb 2024
DOIs	https://doi.org/10.1016/j.eururo.2024.01.002
Publication status	Published - 1 Apr 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Male
Humans
Circulating tumor DNA/genetics
Prostatic neoplasms/pathology
Prostate-specific antigen
Neoplasm recurrence, local/genetics
Prostatectomy

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10.1016/j.eururo.2024.01.002

Pope_2024_Ultra_sensitive_detection_EuroUrology_AAM_CCBY
Copyright © 2024 the Authors. This work has been made available online in accordance with the Rights Retention Strategy This accepted manuscript is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The final published version of this work is available at https://doi.org/10.1016/j.eururo.2024.01.002.
Accepted author manuscript, 376 KBLicence: CC BY

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Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer (dataset)
Pope, B. (Creator), Park, G. (Creator), Lau, E. (Creator), Belic, J. (Creator), Lach, R. (Creator), George, A. (Creator), McCoy, P. (Creator), Nguyen, A. (Creator), Grima, C. (Creator), Campbell, B. (Creator), Jung, C.-H. (Creator), Ditter, E.-J. (Creator), Zhao, H. (Creator), Wedge, D. (Creator), Brewer, D. (Creator), Lynch, A. (Creator), Dev, H. (Creator), Gnanpragasam, V. (Creator), Rosenfeld, N. (Creator), Hovens, C. (Creator), Corcoran, N. (Creator), Massie, C. (Creator) & CR-UK/Prostate Cancer UK, ICGC, The PPCG (Creator), University of St Andrews, 13 Jan 2025
DOI: 10.17630/88156f54-4535-4bcf-a5f1-fe6e3af53be0
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Pope, B., Park, G., Lau, E., Belic, J., Lach, R., George, A., McCoy, P., Nguyen, A., Grima, C., Campbell, B., Jung, C., Ditter, E.-J., Zhao, H., Wedge, D., Brewer, D., Lynch, A., Dev, H., Gnanpragasam, V., Rosenfeld, N., ... CR-UK/Prostate Cancer UK, ICGC, The PPCG (2024). Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer. European Urology, 85(4), 407-410. https://doi.org/10.1016/j.eururo.2024.01.002

@article{26c33aed591d40a99627a2f54b8af6c9,

title = "Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer",

keywords = "Male, Humans, Circulating tumor DNA/genetics, Prostatic neoplasms/pathology, Prostate-specific antigen, Neoplasm recurrence, local/genetics, Prostatectomy",

author = "Bernard Pope and Gahee Park and Edmund Lau and Jelena Belic and Radoslaw Lach and Anne George and Patrick McCoy and Anne Nguyen and Corrina Grima and Bethany Campbell and Chol-hee Jung and Emma-Jane Ditter and Hui Zhao and David Wedge and Daniel Brewer and Andy Lynch and Harveer Dev and Vincent Gnanpragasam and Nitzan Rosenfeld and Christopher Hovens and Niall Corcoran and Charlie Massie and \{CR-UK/Prostate Cancer UK, ICGC, The PPCG\}",

note = "Funding: C.E.M. and H.D. were supported by the Cancer Research UK Cambridge Centre, John Black Charitable Foundation and Prostate Cancer Foundation. H.D. and V.J.G. acknowledge infrastructure support from the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre (BRC-1215- 20014).",

year = "2024",

month = apr,

day = "1",

doi = "10.1016/j.eururo.2024.01.002",

language = "English",

volume = "85",

pages = "407--410",

journal = "European Urology",

issn = "0302-2838",

publisher = "Elsevier",

number = "4",

}

Pope, B, Park, G, Lau, E, Belic, J, Lach, R, George, A, McCoy, P, Nguyen, A, Grima, C, Campbell, B, Jung, C, Ditter, E-J, Zhao, H, Wedge, D, Brewer, D, Lynch, A, Dev, H, Gnanpragasam, V, Rosenfeld, N, Hovens, C, Corcoran, N, Massie, C & CR-UK/Prostate Cancer UK, ICGC, The PPCG 2024, 'Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer', European Urology, vol. 85, no. 4, pp. 407-410. https://doi.org/10.1016/j.eururo.2024.01.002

TY - JOUR

T1 - Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer

AU - Pope, Bernard

AU - Park, Gahee

AU - Lau, Edmund

AU - Belic, Jelena

AU - Lach, Radoslaw

AU - George, Anne

AU - McCoy, Patrick

AU - Nguyen, Anne

AU - Grima, Corrina

AU - Campbell, Bethany

AU - Jung, Chol-hee

AU - Ditter, Emma-Jane

AU - Zhao, Hui

AU - Wedge, David

AU - Brewer, Daniel

AU - Lynch, Andy

AU - Dev, Harveer

AU - Gnanpragasam, Vincent

AU - Rosenfeld, Nitzan

AU - Hovens, Christopher

AU - Corcoran, Niall

AU - Massie, Charlie

AU - CR-UK/Prostate Cancer UK, ICGC, The PPCG

N1 - Funding: C.E.M. and H.D. were supported by the Cancer Research UK Cambridge Centre, John Black Charitable Foundation and Prostate Cancer Foundation. H.D. and V.J.G. acknowledge infrastructure support from the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre (BRC-1215- 20014).

PY - 2024/4/1

Y1 - 2024/4/1

KW - Male

KW - Humans

KW - Circulating tumor DNA/genetics

KW - Prostatic neoplasms/pathology

KW - Prostate-specific antigen

KW - Neoplasm recurrence, local/genetics

KW - Prostatectomy

U2 - 10.1016/j.eururo.2024.01.002

DO - 10.1016/j.eururo.2024.01.002

M3 - Letter

C2 - 38378299

SN - 0302-2838

VL - 85

SP - 407

EP - 410

JO - European Urology

JF - European Urology

IS - 4

ER -

Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer

UN SDGs

Keywords

Access to Document

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Datasets

Ultra-sensitive detection of circulating tumour DNA enriches for patients with greater risk of recurrence in clinically localised prostate cancer (dataset)

Cite this