@inproceedings{fa52b9f4572649deb204569b66f4a1b1,
title = "TPA labelled oligonucleotides for long range distance measurements by EPR",
abstract = "The folding of the RNA and their three-dimensional structure are areas of the great interest of biological and medical research. Besides X-ray, NMR and FRET, Electron Paramagnetic Resonance (EPR) can be applied to elucidate RNA's three-dimensional structure and also the dynamics of the system. Indeed, EPR spectroscopy has already shown to be a powerful technique to characterize the local surrounding of the paramagnetic center in proteins or oligonucleotides(1,2). Pulsed ELectron Double Resonance (PELDOR) enable us to measure long range distances between two nitroxides TPA(1) in DNA(1) and RNA(2) and TEMPA (2 and 2*)(3). The spinlabel was introduced during the solid-phase oligonucleotide synthesis on different nucleobases(4).",
keywords = "PELDOR",
author = "Olga Frolow and Burkhard Endeward and Olav Schiemann and Prisner, {Thomas F} and Engels, {Joachim W}",
year = "2008",
language = "English",
isbn = "978-80-86241-29-6 ",
series = "Collection Symposium Series",
pages = "343--344",
editor = "M. Hocek",
booktitle = "Chemistry of Nucleic Acid Components",
note = "14th Symposium on Chemistry of Nucleic Acid Components ; Conference date: 08-06-2008 Through 13-06-2008",
}