Toxicity of Copper(I)-NHC Complexes Against Human Tumor Cells: Induction of Cell Cycle Arrest, Apoptosis, and DNA Cleavage

Marie-Laure Teyssot, Anne-Sophie Jarrousse, Aurelien Chevry, Angelique De Haze, Claude Beaudoin, Michele Manin, Steven Patrick Nolan, Silvia Diez-Gonzalez, Laurent Morel, Arnaud Gautier

Research output: Contribution to journalArticlepeer-review

100 Citations (Scopus)
Original languageEnglish
Pages (from-to)314-318
Number of pages5
JournalChemistry - A European Journal
Volume15
Issue number2
DOIs
Publication statusPublished - 2009

Keywords

  • antitumor agents
  • apoptosis
  • carbenes
  • cell cycle
  • HETEROCYCLIC CARBENE COMPLEXES
  • CANCER-CELLS
  • NUCLEASE ACTIVITY
  • COPPER-COMPLEXES
  • OXIDATION
  • OXYGEN
  • PALLADIUM
  • EFFICIENT
  • PATHWAY
  • DAMAGE

Cite this