Thrombotic thrombocytopenic purpura mimicking acute small bowel Crohn's disease

P J Winwood; J P Iredale; P J Williamson; M Lesna; C A Loehry

Thrombotic thrombocytopenic purpura mimicking acute small bowel Crohn's disease

P J Winwood, J P Iredale, P J Williamson, M Lesna, C A Loehry

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

A 39 year old woman presented with a short history of bloody diarrhoea. She subsequently developed microangiopathic haemolysis, platelet consumption, and renal impairment. Initial investigations suggested underlying Crohn's disease of the terminal ileum complicated by sepsis and disseminated intravascular coagulation. However, after resection of a perforated caecum and terminal ileum, the diagnosis of thrombotic thrombocytopenic purpura was made. There was weak serological evidence of yersinia infection, this may have caused the early localisation of the lesions to the terminal ileum. This is believed to be the first report of thrombotic thrombocytopenic purpura affecting the small bowel alone at presentation.

Original language	English
Pages (from-to)	857-9
Number of pages	3
Journal	Gut
Volume	33
Issue number	6
Publication status	Published - Jun 1992

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Crohn Disease/diagnosis
Diagnosis, Differential
Disseminated Intravascular Coagulation/complications
Female
Humans
Ileal Diseases/diagnosis
Infant
Purpura, Thrombotic Thrombocytopenic/complications
Yersinia Infections/complications
Yersinia enterocolitica

Cite this

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title = "Thrombotic thrombocytopenic purpura mimicking acute small bowel Crohn's disease",

abstract = "A 39 year old woman presented with a short history of bloody diarrhoea. She subsequently developed microangiopathic haemolysis, platelet consumption, and renal impairment. Initial investigations suggested underlying Crohn's disease of the terminal ileum complicated by sepsis and disseminated intravascular coagulation. However, after resection of a perforated caecum and terminal ileum, the diagnosis of thrombotic thrombocytopenic purpura was made. There was weak serological evidence of yersinia infection, this may have caused the early localisation of the lesions to the terminal ileum. This is believed to be the first report of thrombotic thrombocytopenic purpura affecting the small bowel alone at presentation.",

keywords = "Crohn Disease/diagnosis, Diagnosis, Differential, Disseminated Intravascular Coagulation/complications, Female, Humans, Ileal Diseases/diagnosis, Infant, Purpura, Thrombotic Thrombocytopenic/complications, Yersinia Infections/complications, Yersinia enterocolitica",

author = "Winwood, \{P J\} and Iredale, \{J P\} and Williamson, \{P J\} and M Lesna and Loehry, \{C A\}",

year = "1992",

month = jun,

language = "English",

volume = "33",

pages = "857--9",

journal = "Gut",

issn = "0017-5749",

publisher = "BMJ Publishing Group",

number = "6",

}

TY - JOUR

T1 - Thrombotic thrombocytopenic purpura mimicking acute small bowel Crohn's disease

AU - Winwood, P J

AU - Iredale, J P

AU - Williamson, P J

AU - Lesna, M

AU - Loehry, C A

PY - 1992/6

Y1 - 1992/6

N2 - A 39 year old woman presented with a short history of bloody diarrhoea. She subsequently developed microangiopathic haemolysis, platelet consumption, and renal impairment. Initial investigations suggested underlying Crohn's disease of the terminal ileum complicated by sepsis and disseminated intravascular coagulation. However, after resection of a perforated caecum and terminal ileum, the diagnosis of thrombotic thrombocytopenic purpura was made. There was weak serological evidence of yersinia infection, this may have caused the early localisation of the lesions to the terminal ileum. This is believed to be the first report of thrombotic thrombocytopenic purpura affecting the small bowel alone at presentation.

AB - A 39 year old woman presented with a short history of bloody diarrhoea. She subsequently developed microangiopathic haemolysis, platelet consumption, and renal impairment. Initial investigations suggested underlying Crohn's disease of the terminal ileum complicated by sepsis and disseminated intravascular coagulation. However, after resection of a perforated caecum and terminal ileum, the diagnosis of thrombotic thrombocytopenic purpura was made. There was weak serological evidence of yersinia infection, this may have caused the early localisation of the lesions to the terminal ileum. This is believed to be the first report of thrombotic thrombocytopenic purpura affecting the small bowel alone at presentation.

KW - Crohn Disease/diagnosis

KW - Diagnosis, Differential

KW - Disseminated Intravascular Coagulation/complications

KW - Female

KW - Humans

KW - Ileal Diseases/diagnosis

KW - Infant

KW - Purpura, Thrombotic Thrombocytopenic/complications

KW - Yersinia Infections/complications

KW - Yersinia enterocolitica

UR - https://www.scopus.com/pages/publications/0026608271

M3 - Article

C2 - 1624173

SN - 0017-5749

VL - 33

SP - 857

EP - 859

JO - Gut

JF - Gut

IS - 6

ER -

Thrombotic thrombocytopenic purpura mimicking acute small bowel Crohn's disease

Abstract

UN SDGs

Keywords

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