The vicinal F-C-C-F moiety as a tool for influencing peptide conformation

M Schuler, D O'Hagan, A M Z Slawin

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)

Abstract

Diastereoisomers of bis(amino acid amides) of 2,3-difluorosuccinic acid have been prepared and the erythro- and threoisomers display very different conformations.

Original languageEnglish
Pages (from-to)4324-4326
Number of pages3
JournalChemical Communications
Issue number34
DOIs
Publication statusPublished - 2005

Keywords

  • BETA-PEPTIDES
  • FLUORINE
  • NMR

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