The vicinal F-C-C-F moiety as a tool for influencing peptide conformation

M  Schuler; D  O'Hagan; A M Z  Slawin

doi:10.1039/b506010a

The vicinal F-C-C-F moiety as a tool for influencing peptide conformation

M Schuler, D O'Hagan, A M Z Slawin

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Diastereoisomers of bis(amino acid amides) of 2,3-difluorosuccinic acid have been prepared and the erythro- and threoisomers display very different conformations.

Original language	English
Pages (from-to)	4324-4326
Number of pages	3
Journal	Chemical Communications
Issue number	34
DOIs	https://doi.org/10.1039/b506010a
Publication status	Published - 2005

Keywords

BETA-PEPTIDES
FLUORINE
NMR

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10.1039/b506010a

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title = "The vicinal F-C-C-F moiety as a tool for influencing peptide conformation",

abstract = "Diastereoisomers of bis(amino acid amides) of 2,3-difluorosuccinic acid have been prepared and the erythro- and threoisomers display very different conformations.",

keywords = "BETA-PEPTIDES, FLUORINE, NMR",

author = "M Schuler and D O'Hagan and Slawin, {A M Z}",

year = "2005",

doi = "10.1039/b506010a",

language = "English",

pages = "4324--4326",

journal = "Chemical Communications",

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AU - Schuler, M

AU - O'Hagan, D

AU - Slawin, A M Z

PY - 2005

Y1 - 2005

N2 - Diastereoisomers of bis(amino acid amides) of 2,3-difluorosuccinic acid have been prepared and the erythro- and threoisomers display very different conformations.

AB - Diastereoisomers of bis(amino acid amides) of 2,3-difluorosuccinic acid have been prepared and the erythro- and threoisomers display very different conformations.

KW - BETA-PEPTIDES

KW - FLUORINE

KW - NMR

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U2 - 10.1039/b506010a

DO - 10.1039/b506010a

M3 - Article

SN - 1359-7345

SP - 4324

EP - 4326

JO - Chemical Communications

JF - Chemical Communications

IS - 34

ER -

The vicinal F-C-C-F moiety as a tool for influencing peptide conformation

Abstract

Keywords

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