The Urbilaterian Super-Hox cluster.

T Butts, PWH Holland, David Ellard Keith Ferrier

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

Comparison of whole genome sequences of representative animals enables reconstruction of the ancestral bilaterian genome: the starting point from which most extant animal lineages evolved. The Hox gene cluster patterns the anterior-posterior axis of bilaterians. Here we show that this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the ancestral bilaterian. This Super-Hox cluster contained at least eight genes alongside the core Hox genes ('EuHox' genes).

Original languageEnglish
Pages (from-to)259 - 262
Number of pages4
JournalTrends in Genetics
Volume24
Issue number6
DOIs
Publication statusPublished - Jun 2008

Keywords

  • HOMEOBOX GENE CLUSTERS
  • NEMATOSTELLA-VECTENSIS
  • PARAHOX GENES
  • EVOLUTION
  • AMPHIOXUS
  • PHYLOGENY
  • EVX

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