The Urbilaterian Super-Hox cluster.

T Butts; PWH Holland; David Ellard Keith Ferrier

doi:10.1016/j.tig.2007.09.006

The Urbilaterian Super-Hox cluster.

T Butts, PWH Holland, David Ellard Keith Ferrier

School of Biology

Research output: Contribution to journal › Article › peer-review

Abstract

Comparison of whole genome sequences of representative animals enables reconstruction of the ancestral bilaterian genome: the starting point from which most extant animal lineages evolved. The Hox gene cluster patterns the anterior-posterior axis of bilaterians. Here we show that this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the ancestral bilaterian. This Super-Hox cluster contained at least eight genes alongside the core Hox genes ('EuHox' genes).

Original language	English
Pages (from-to)	259 - 262
Number of pages	4
Journal	Trends in Genetics
Volume	24
Issue number	6
DOIs	https://doi.org/10.1016/j.tig.2007.09.006
Publication status	Published - Jun 2008

Keywords

HOMEOBOX GENE CLUSTERS
NEMATOSTELLA-VECTENSIS
PARAHOX GENES
EVOLUTION
AMPHIOXUS
PHYLOGENY
EVX

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10.1016/j.tig.2007.09.006

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title = "The Urbilaterian Super-Hox cluster.",

abstract = "Comparison of whole genome sequences of representative animals enables reconstruction of the ancestral bilaterian genome: the starting point from which most extant animal lineages evolved. The Hox gene cluster patterns the anterior-posterior axis of bilaterians. Here we show that this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the ancestral bilaterian. This Super-Hox cluster contained at least eight genes alongside the core Hox genes ('EuHox' genes).",

keywords = "HOMEOBOX GENE CLUSTERS, NEMATOSTELLA-VECTENSIS, PARAHOX GENES, EVOLUTION, AMPHIOXUS, PHYLOGENY, EVX",

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year = "2008",

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AU - Holland, PWH

AU - Ferrier, David Ellard Keith

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AB - Comparison of whole genome sequences of representative animals enables reconstruction of the ancestral bilaterian genome: the starting point from which most extant animal lineages evolved. The Hox gene cluster patterns the anterior-posterior axis of bilaterians. Here we show that this cluster was embedded within a larger homeobox gene cluster, the Super-Hox cluster, in the ancestral bilaterian. This Super-Hox cluster contained at least eight genes alongside the core Hox genes ('EuHox' genes).

KW - HOMEOBOX GENE CLUSTERS

KW - NEMATOSTELLA-VECTENSIS

KW - PARAHOX GENES

KW - EVOLUTION

KW - AMPHIOXUS

KW - PHYLOGENY

KW - EVX

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DO - 10.1016/j.tig.2007.09.006

M3 - Article

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SP - 259

EP - 262

JO - Trends in Genetics

JF - Trends in Genetics

IS - 6

ER -

The Urbilaterian Super-Hox cluster.

Abstract

Keywords

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