The synthesis of multiply C-13-labelled plant and mammalian lignans as internal standards for LC-MS and GC-MS analysis

T  Fryatt; N P  Botting

doi:10.1002/jlcr.1007

The synthesis of multiply C-13-labelled plant and mammalian lignans as internal standards for LC-MS and GC-MS analysis

T Fryatt, N P Botting

Research output: Contribution to journal › Article › peer-review

Abstract

The syntheses of multiply C-13-labelled derivatives of the two mammalian lignans, enterolactone and enterodiol, and two of their plant lignan precursors, secoisolariciresinol and matairesinol, are described. Three C-13 atoms were incorporated into each lignan using potassium [C-13]cyanide as the source for all of the C-13 atoms. The compounds were prepared for use as internal standards in the LC-MS and GC-MS analysis of lignans. Copyright (c) 2005 John Wiley & Sons, Ltd.

Original language	English
Pages (from-to)	951-969
Number of pages	19
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	48
DOIs	https://doi.org/10.1002/jlcr.1007
Publication status	Published - Nov 2005

Keywords

lignans
phytoestrogens
enterolactone
enterodiol
analysis
<H-2>-LABELED URINARY LIGNANS
MASS-SPECTROMETRY
BREAST-CANCER
SERUM CONCENTRATIONS
ENTEROLACTONE
RISK
QUANTIFICATION
PHYTOESTROGENS
IDENTIFICATION
ISOFLAVONOIDS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/jlcr.1007

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abstract = "The syntheses of multiply C-13-labelled derivatives of the two mammalian lignans, enterolactone and enterodiol, and two of their plant lignan precursors, secoisolariciresinol and matairesinol, are described. Three C-13 atoms were incorporated into each lignan using potassium [C-13]cyanide as the source for all of the C-13 atoms. The compounds were prepared for use as internal standards in the LC-MS and GC-MS analysis of lignans. Copyright (c) 2005 John Wiley & Sons, Ltd.",

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author = "T Fryatt and Botting, {N P}",

year = "2005",

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doi = "10.1002/jlcr.1007",

language = "English",

volume = "48",

pages = "951--969",

journal = "Journal of Labelled Compounds and Radiopharmaceuticals",

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TY - JOUR

T1 - The synthesis of multiply C-13-labelled plant and mammalian lignans as internal standards for LC-MS and GC-MS analysis

AU - Fryatt, T

AU - Botting, N P

PY - 2005/11

Y1 - 2005/11

N2 - The syntheses of multiply C-13-labelled derivatives of the two mammalian lignans, enterolactone and enterodiol, and two of their plant lignan precursors, secoisolariciresinol and matairesinol, are described. Three C-13 atoms were incorporated into each lignan using potassium [C-13]cyanide as the source for all of the C-13 atoms. The compounds were prepared for use as internal standards in the LC-MS and GC-MS analysis of lignans. Copyright (c) 2005 John Wiley & Sons, Ltd.

AB - The syntheses of multiply C-13-labelled derivatives of the two mammalian lignans, enterolactone and enterodiol, and two of their plant lignan precursors, secoisolariciresinol and matairesinol, are described. Three C-13 atoms were incorporated into each lignan using potassium [C-13]cyanide as the source for all of the C-13 atoms. The compounds were prepared for use as internal standards in the LC-MS and GC-MS analysis of lignans. Copyright (c) 2005 John Wiley & Sons, Ltd.

KW - lignans

KW - phytoestrogens

KW - enterolactone

KW - enterodiol

KW - analysis

KW - <H-2>-LABELED URINARY LIGNANS

KW - MASS-SPECTROMETRY

KW - BREAST-CANCER

KW - SERUM CONCENTRATIONS

KW - ENTEROLACTONE

KW - RISK

KW - QUANTIFICATION

KW - PHYTOESTROGENS

KW - IDENTIFICATION

KW - ISOFLAVONOIDS

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U2 - 10.1002/jlcr.1007

DO - 10.1002/jlcr.1007

M3 - Article

SN - 0362-4803

VL - 48

SP - 951

EP - 969

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

ER -

The synthesis of multiply C-13-labelled plant and mammalian lignans as internal standards for LC-MS and GC-MS analysis

Abstract

Keywords

UN SDGs

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