The synthesis of isotopically labelled glucoraphanin for metabolic studies

John J. Morrison; Nigel P. Botting

doi:10.1016/j.tetlet.2007.01.107

The synthesis of isotopically labelled glucoraphanin for metabolic studies

John J. Morrison, Nigel P. Botting

Research output: Contribution to journal › Article › peer-review

Abstract

The first synthesis of a stable isotopically labelled derivative of the glucosinolate glucoraphanin, namely [10-C-13, 11,12-H-2(5)]glucoraphanin, is described. This also represents the first total chemical synthesis of glucoraphanin itself. (c) 2007 Published by Elsevier Ltd.

Original language	English
Pages (from-to)	1891-1894
Number of pages	4
Journal	Tetrahedron Letters
Volume	48
DOIs	https://doi.org/10.1016/j.tetlet.2007.01.107
Publication status	Published - 12 Mar 2007

Keywords

glucosinolates
isothiocyanates
glucoraphanin
cancer prevention
sulforaphane

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.tetlet.2007.01.107

Cite this

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title = "The synthesis of isotopically labelled glucoraphanin for metabolic studies",

abstract = "The first synthesis of a stable isotopically labelled derivative of the glucosinolate glucoraphanin, namely [10-C-13, 11,12-H-2(5)]glucoraphanin, is described. This also represents the first total chemical synthesis of glucoraphanin itself. (c) 2007 Published by Elsevier Ltd.",

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author = "Morrison, \{John J.\} and Botting, \{Nigel P.\}",

year = "2007",

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doi = "10.1016/j.tetlet.2007.01.107",

language = "English",

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journal = "Tetrahedron Letters",

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AU - Morrison, John J.

AU - Botting, Nigel P.

PY - 2007/3/12

Y1 - 2007/3/12

N2 - The first synthesis of a stable isotopically labelled derivative of the glucosinolate glucoraphanin, namely [10-C-13, 11,12-H-2(5)]glucoraphanin, is described. This also represents the first total chemical synthesis of glucoraphanin itself. (c) 2007 Published by Elsevier Ltd.

AB - The first synthesis of a stable isotopically labelled derivative of the glucosinolate glucoraphanin, namely [10-C-13, 11,12-H-2(5)]glucoraphanin, is described. This also represents the first total chemical synthesis of glucoraphanin itself. (c) 2007 Published by Elsevier Ltd.

KW - glucosinolates

KW - isothiocyanates

KW - glucoraphanin

KW - cancer prevention

KW - sulforaphane

UR - https://www.scopus.com/pages/publications/33846921525

U2 - 10.1016/j.tetlet.2007.01.107

DO - 10.1016/j.tetlet.2007.01.107

M3 - Article

SN - 0040-4039

VL - 48

SP - 1891

EP - 1894

JO - Tetrahedron Letters

JF - Tetrahedron Letters

ER -

The synthesis of isotopically labelled glucoraphanin for metabolic studies

Abstract

Keywords

UN SDGs

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