The synthesis of glucosinolates deuterium labelled in the glucose fragment

Avril A. B. Robertson; Nigel P. Botting

doi:10.1002/jlcr.1141

The synthesis of glucosinolates deuterium labelled in the glucose fragment

Avril A. B. Robertson, Nigel P. Botting

Research output: Contribution to journal › Article › peer-review

Abstract

A facile synthesis is described for 2,3,4,6-tetra-O-acetyl-thio-beta-D-[1-H-2,6-H-2(2)]glucopyranose, which has been used to make an isotopically labelled desulphoglucosinolate, [1'-H-2,6'-H-2(2)]desulfogluconasturtiln. This isotopically labelled building block can be employed to make any glucosinolate or desulfoglucosinolate for use as internal standards for MS based analytical methods. Copyright (c) 2006 John Wiley & Sons, Ltd.

Original language	English
Pages (from-to)	1201-1211
Number of pages	11
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	49
DOIs	https://doi.org/10.1002/jlcr.1141
Publication status	Published - Nov 2006

Keywords

glucosinolates
isothiocyanates
gluconasturtiin
cancer prevention
CANCER PREVENTION
ISOTHIOCYANATES
VEGETABLES
APOPTOSIS
PRODUCTS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/jlcr.1141

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title = "The synthesis of glucosinolates deuterium labelled in the glucose fragment",

abstract = "A facile synthesis is described for 2,3,4,6-tetra-O-acetyl-thio-beta-D-[1-H-2,6-H-2(2)]glucopyranose, which has been used to make an isotopically labelled desulphoglucosinolate, [1'-H-2,6'-H-2(2)]desulfogluconasturtiln. This isotopically labelled building block can be employed to make any glucosinolate or desulfoglucosinolate for use as internal standards for MS based analytical methods. Copyright (c) 2006 John Wiley & Sons, Ltd.",

keywords = "glucosinolates, isothiocyanates, gluconasturtiin, cancer prevention, CANCER PREVENTION, ISOTHIOCYANATES, VEGETABLES, APOPTOSIS, PRODUCTS",

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year = "2006",

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doi = "10.1002/jlcr.1141",

language = "English",

volume = "49",

pages = "1201--1211",

journal = "Journal of Labelled Compounds and Radiopharmaceuticals",

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AU - Robertson, Avril A. B.

AU - Botting, Nigel P.

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N2 - A facile synthesis is described for 2,3,4,6-tetra-O-acetyl-thio-beta-D-[1-H-2,6-H-2(2)]glucopyranose, which has been used to make an isotopically labelled desulphoglucosinolate, [1'-H-2,6'-H-2(2)]desulfogluconasturtiln. This isotopically labelled building block can be employed to make any glucosinolate or desulfoglucosinolate for use as internal standards for MS based analytical methods. Copyright (c) 2006 John Wiley & Sons, Ltd.

AB - A facile synthesis is described for 2,3,4,6-tetra-O-acetyl-thio-beta-D-[1-H-2,6-H-2(2)]glucopyranose, which has been used to make an isotopically labelled desulphoglucosinolate, [1'-H-2,6'-H-2(2)]desulfogluconasturtiln. This isotopically labelled building block can be employed to make any glucosinolate or desulfoglucosinolate for use as internal standards for MS based analytical methods. Copyright (c) 2006 John Wiley & Sons, Ltd.

KW - glucosinolates

KW - isothiocyanates

KW - gluconasturtiin

KW - cancer prevention

KW - CANCER PREVENTION

KW - ISOTHIOCYANATES

KW - VEGETABLES

KW - APOPTOSIS

KW - PRODUCTS

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U2 - 10.1002/jlcr.1141

DO - 10.1002/jlcr.1141

M3 - Article

SN - 0362-4803

VL - 49

SP - 1201

EP - 1211

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

ER -

The synthesis of glucosinolates deuterium labelled in the glucose fragment

Abstract

Keywords

UN SDGs

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