The saponins - polar isoprenoids with important and diverse biological activities

Anne Osbourn*, Rebecca J. M. Goss, Robert A. Field

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

159 Citations (Scopus)

Abstract

Saponins are polar molecules that consist of a triterpene or steroid aglycone with one or more sugar chains. They are one of the most numerous and diverse groups of plant natural products. These molecules have important ecological and agronomic functions, contributing to pest and pathogen resistance and to food quality in crop plants. They also have a wide range of commercial applications in the food, cosmetics and pharmaceutical sectors. Although primarily found in plants, saponins are produced by certain other organisms, including starfish and sea cucumbers. The underexplored biodiversity of this class of natural products is likely to prove to be a vital resource for discovery of high-value compounds. This review will focus on the biological activity of some of the best-studied examples of saponins, on the relationship between structure and function, and on prospects for synthesis of "designer" saponins.

Original languageEnglish
Pages (from-to)1261-1268
Number of pages8
JournalNatural Product Reports
Volume28
Issue number7
DOIs
Publication statusPublished - 2011

Keywords

  • POTATO GLYCOALKALOIDS
  • DISEASE RESISTANCE
  • PLANT DEFENSE
  • QUILLAJA-SAPONARIA
  • SERINE CARBOXYPEPTIDASE
  • LETTUCE ROOTS
  • CHROMOSAPONIN-I
  • LEGUME MEDICAGO-TRUNCATULA
  • NATURAL-PRODUCTS
  • CARBOXYPEPTIDASE-LIKE PROTEIN

Fingerprint

Dive into the research topics of 'The saponins - polar isoprenoids with important and diverse biological activities'. Together they form a unique fingerprint.

Cite this