The role of silver additives in gold-mediated C-H functionalisation

Scott R. Patrick; Ine I. F. Boogaerts; Sylvain Gaillard; Alexandra M. Z. Slawin; Steven P. Nolan

doi:10.3762/bjoc.7.102

The role of silver additives in gold-mediated C-H functionalisation

Scott R. Patrick, Ine I. F. Boogaerts, Sylvain Gaillard, Alexandra M. Z. Slawin, Steven P. Nolan

Research output: Contribution to journal › Article › peer-review

Abstract

The role of silver additives is examined in the context of gold-mediated functionalisation of aromatic C-H bonds. Doubt is cast on the commonly cited route of halide abstraction from gold and evidence of substrate activation is given.

Original language	English
Pages (from-to)	892-896
Number of pages	5
Journal	Beilstein Journal of Organic Chemistry
Volume	7
DOIs	https://doi.org/10.3762/bjoc.7.102
Publication status	Published - 1 Jul 2011

Keywords

C-H functionalisation
Gold catalyst
Halide abstraction
N-heterocyclic carbene
Silver salt
Substrate activation
N-Heterocyclic carbenes
Bond formation
Catalysis
Arylation
Complexes
Acid

Access to Document

10.3762/bjoc.7.102

Patricketal2011BeilsteinJOrgChem7SilverAdditives
© 2011 Patrick et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Final published version, 442 KB

Molecular assembly using gold catalysis: Molecular assembly using gold catalysis
Nolan, S. P. (PI)
EPSRC
1/01/10 → 31/12/12
Project: Standard
FUNCAT: EU FP7 ERC Advanced Grant - FUNCAT - Fundamental Studies in Organometallic Chemistry and Homogeneous Catalysis
Nolan, S. P. (PI)
European Research Council
1/01/09 → 31/12/14
Project: Standard

Cite this

@article{c18817aff0634412b7f06e27f2c5a1b0,

title = "The role of silver additives in gold-mediated C-H functionalisation",

abstract = "The role of silver additives is examined in the context of gold-mediated functionalisation of aromatic C-H bonds. Doubt is cast on the commonly cited route of halide abstraction from gold and evidence of substrate activation is given.",

keywords = "C-H functionalisation, Gold catalyst, Halide abstraction, N-heterocyclic carbene, Silver salt, Substrate activation, N-Heterocyclic carbenes, Bond formation, Catalysis, Arylation, Complexes, Acid",

author = "Patrick, {Scott R.} and Boogaerts, {Ine I. F.} and Sylvain Gaillard and Slawin, {Alexandra M. Z.} and Nolan, {Steven P.}",

year = "2011",

month = jul,

day = "1",

doi = "10.3762/bjoc.7.102",

language = "English",

volume = "7",

pages = "892--896",

journal = "Beilstein Journal of Organic Chemistry",

issn = "1860-5397",

publisher = "Beilstein-Institut Zur Forderung der Chemischen Wissenschaften",

}

TY - JOUR

T1 - The role of silver additives in gold-mediated C-H functionalisation

AU - Patrick, Scott R.

AU - Boogaerts, Ine I. F.

AU - Gaillard, Sylvain

AU - Slawin, Alexandra M. Z.

AU - Nolan, Steven P.

PY - 2011/7/1

Y1 - 2011/7/1

N2 - The role of silver additives is examined in the context of gold-mediated functionalisation of aromatic C-H bonds. Doubt is cast on the commonly cited route of halide abstraction from gold and evidence of substrate activation is given.

AB - The role of silver additives is examined in the context of gold-mediated functionalisation of aromatic C-H bonds. Doubt is cast on the commonly cited route of halide abstraction from gold and evidence of substrate activation is given.

KW - C-H functionalisation

KW - Gold catalyst

KW - Halide abstraction

KW - N-heterocyclic carbene

KW - Silver salt

KW - Substrate activation

KW - N-Heterocyclic carbenes

KW - Bond formation

KW - Catalysis

KW - Arylation

KW - Complexes

KW - Acid

U2 - 10.3762/bjoc.7.102

DO - 10.3762/bjoc.7.102

M3 - Article

SN - 1860-5397

VL - 7

SP - 892

EP - 896

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

ER -

The role of silver additives in gold-mediated C-H functionalisation

Abstract

Keywords

Access to Document

Fingerprint

Projects

Molecular assembly using gold catalysis: Molecular assembly using gold catalysis

FUNCAT: EU FP7 ERC Advanced Grant - FUNCAT - Fundamental Studies in Organometallic Chemistry and Homogeneous Catalysis

Cite this