The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under 	  	  Ultrasound-Assisted Olefin Cross-Metathesis

Ozkan Sari; Manabu Hamada; Vincent Roy; Steven Patrick Nolan; Luigi Agrofoglio

doi:10.1021/ol401922r

The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under Ultrasound-Assisted Olefin Cross-Metathesis

Ozkan Sari, Manabu Hamada, Vincent Roy, Steven Patrick Nolan, Luigi Agrofoglio

Research output: Contribution to journal › Article › peer-review

Abstract

Intermolecular ultrasound-assisted olefin cross-metathesis is reported. This approach allows an easy access to challenging trisubstituted alkenyl
nucleoside phosphonates. Regioselective chemoenzymatic deacetylation and Mitsunobu coupling are also described.

Original language	English
Pages (from-to)	4390-4393
Number of pages	4
Journal	Organic Letters
Volume	15
Issue number	17
Early online date	20 Aug 2013
DOIs	https://doi.org/10.1021/ol401922r
Publication status	Published - 2013

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title = "The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under Ultrasound-Assisted Olefin Cross-Metathesis",

abstract = "Intermolecular ultrasound-assisted olefin cross-metathesis is reported. This approach allows an easy access to challenging trisubstituted alkenylnucleoside phosphonates. Regioselective chemoenzymatic deacetylation and Mitsunobu coupling are also described.",

author = "Ozkan Sari and Manabu Hamada and Vincent Roy and Nolan, {Steven Patrick} and Luigi Agrofoglio",

year = "2013",

doi = "10.1021/ol401922r",

language = "English",

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journal = "Organic Letters",

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T1 - The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under Ultrasound-Assisted Olefin Cross-Metathesis

AU - Sari, Ozkan

AU - Hamada, Manabu

AU - Roy, Vincent

AU - Nolan, Steven Patrick

AU - Agrofoglio, Luigi

PY - 2013

Y1 - 2013

N2 - Intermolecular ultrasound-assisted olefin cross-metathesis is reported. This approach allows an easy access to challenging trisubstituted alkenylnucleoside phosphonates. Regioselective chemoenzymatic deacetylation and Mitsunobu coupling are also described.

AB - Intermolecular ultrasound-assisted olefin cross-metathesis is reported. This approach allows an easy access to challenging trisubstituted alkenylnucleoside phosphonates. Regioselective chemoenzymatic deacetylation and Mitsunobu coupling are also described.

U2 - 10.1021/ol401922r

DO - 10.1021/ol401922r

M3 - Article

SN - 1523-7060

VL - 15

SP - 4390

EP - 4393

JO - Organic Letters

JF - Organic Letters

IS - 17

ER -

The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under Ultrasound-Assisted Olefin Cross-Metathesis

Abstract

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