The mathematical modelling of wound healing and tumour growth: two sides of the same coin

M. A. J. Chaplain, H. M. Byrne

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Over the last thirty years or so, mathematical biology, i.e. the application of mathematics and mathematical techniques to problems arising in biology, has grown rapidly as a subject in its own right. In more recent years a very important subset of biomathematics which has emerged may be defined as "theoretical medicine" i.e. the application of mathematical techniques and modeling skills to problems arising specifically from the medical sciences. Applications of mathematics are to be found in areas such as biomechanics, modeling the heart, modeling the cardiovascular system, pharmacokinetics, chemotherapy and epidemiology to name but a few. In this article we wish to discuss the contribution that mathematical modeling has been making recently in modeling two very important processes - tumor growth and development and wound healing or tissue repair - and to present an overview of articles in these areas as well as focus on specific models of angiogenesis, a crucial part of both processes.
Original languageEnglish
Pages (from-to)42-48
Number of pages7
JournalWounds: a Compendium of Clinical Research and Practice
Volume8
Issue number2
Publication statusPublished - 1996

Keywords

  • Mathematical modelling
  • Wound healing
  • Tumour growth

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