The Importance of Ligand Steric Effects on Transmetalation

Matthew L Clarke; Mattias Heydt

doi:10.1021/om050724p

The Importance of Ligand Steric Effects on Transmetalation

Research output: Contribution to journal › Article › peer-review

Abstract

A very striking phosphine steric effect on the rate of transmetalation of phenyl zinc bromide to platinum complexes has been observed: most Pt(11) complexes of type (Pt(diphosphine)(Ph)Br] react with PhZnBr rapidly, the slowest reacting complexes being those derived from bis(dicyclohexylphosphino)ethane and bis(di-tent-butylphosphino)xylene.

Original language	English
Pages (from-to)	6475-6478
Number of pages	4
Journal	Organometallics
Volume	24
Issue number	26
DOIs	https://doi.org/10.1021/om050724p
Publication status	Published - 19 Dec 2005

Keywords

CROSS-COUPLING REACTIONS
STILLE REACTION
REDUCTIVE ELIMINATION
OXIDATIVE ADDITION
ARYL CHLORIDES
STRUCTURAL-CHARACTERIZATION
PALLADIUM(0) COMPLEXES
ARYLBORONIC ACIDS
KINETIC-ANALYSIS
MECHANISM

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10.1021/om050724p

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title = "The Importance of Ligand Steric Effects on Transmetalation",

abstract = "A very striking phosphine steric effect on the rate of transmetalation of phenyl zinc bromide to platinum complexes has been observed: most Pt(11) complexes of type (Pt(diphosphine)(Ph)Br] react with PhZnBr rapidly, the slowest reacting complexes being those derived from bis(dicyclohexylphosphino)ethane and bis(di-tent-butylphosphino)xylene.",

keywords = "CROSS-COUPLING REACTIONS, STILLE REACTION, REDUCTIVE ELIMINATION, OXIDATIVE ADDITION, ARYL CHLORIDES, STRUCTURAL-CHARACTERIZATION, PALLADIUM(0) COMPLEXES, ARYLBORONIC ACIDS, KINETIC-ANALYSIS, MECHANISM",

author = "Clarke, {Matthew L} and Mattias Heydt",

year = "2005",

month = dec,

day = "19",

doi = "10.1021/om050724p",

language = "English",

volume = "24",

pages = "6475--6478",

journal = "Organometallics",

issn = "0276-7333",

publisher = "American Chemical Society (ACS)",

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T1 - The Importance of Ligand Steric Effects on Transmetalation

AU - Clarke, Matthew L

AU - Heydt, Mattias

PY - 2005/12/19

Y1 - 2005/12/19

N2 - A very striking phosphine steric effect on the rate of transmetalation of phenyl zinc bromide to platinum complexes has been observed: most Pt(11) complexes of type (Pt(diphosphine)(Ph)Br] react with PhZnBr rapidly, the slowest reacting complexes being those derived from bis(dicyclohexylphosphino)ethane and bis(di-tent-butylphosphino)xylene.

AB - A very striking phosphine steric effect on the rate of transmetalation of phenyl zinc bromide to platinum complexes has been observed: most Pt(11) complexes of type (Pt(diphosphine)(Ph)Br] react with PhZnBr rapidly, the slowest reacting complexes being those derived from bis(dicyclohexylphosphino)ethane and bis(di-tent-butylphosphino)xylene.

KW - CROSS-COUPLING REACTIONS

KW - STILLE REACTION

KW - REDUCTIVE ELIMINATION

KW - OXIDATIVE ADDITION

KW - ARYL CHLORIDES

KW - STRUCTURAL-CHARACTERIZATION

KW - PALLADIUM(0) COMPLEXES

KW - ARYLBORONIC ACIDS

KW - KINETIC-ANALYSIS

KW - MECHANISM

UR - http://www.scopus.com/inward/record.url?scp=30344448268&partnerID=8YFLogxK

U2 - 10.1021/om050724p

DO - 10.1021/om050724p

M3 - Article

SN - 0276-7333

VL - 24

SP - 6475

EP - 6478

JO - Organometallics

JF - Organometallics

IS - 26

ER -

The Importance of Ligand Steric Effects on Transmetalation

Abstract

Keywords

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