The impact of two-component sensorial network in staphylococcal speciation

Beatriz Rapun-Araiz, Andreas F Haag, Cristina Solano*, Iñigo Lasa

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

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Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. Differences in the content of two-component systems are related with the capacity of the bacteria to colonize different niches or improve the efficiency to grow under the conditions of the existing niche. This review highlights differences in the TCS content between Staphylococcus aureus and Staphylococcus saprophyticus as a case study to exemplify how the ability to sense and respond to the environment is relevant for bacterial capacity to colonize and survive in/on different body surfaces.
Original languageEnglish
Pages (from-to)40-47
Number of pages8
JournalCurrent Opinion in Microbiology
Early online date19 Mar 2020
Publication statusPublished - Jun 2020


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