TY - JOUR
T1 - The impact of two-component sensorial network in staphylococcal speciation
AU - Rapun-Araiz, Beatriz
AU - Haag, Andreas F
AU - Solano, Cristina
AU - Lasa, Iñigo
N1 - B.R is recipient of a PhD grant from Universidad Pública de Navarra. Work in the Laboratory of Microbial Pathogenesis is funded by the Spanish Ministry of Science, Innovation and Universities grant BIO2017-83035-R Agencia Española de Investigación/Fondo Europeo de Desarrollo Regional, European Union. A.F.H. is supported by the European Research Council ERC under the European Union’s Horizon 2020 research and innovation program Grant Agreement ERC-ADG-2014 Proposal n° 670932 Dut-signal from EU awarded to José R. Penadés) and was the recipient of a Tenovus Project Grant (S16-12).
PY - 2020/6
Y1 - 2020/6
N2 - Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. Differences in the content of two-component systems are related with the capacity of the bacteria to colonize different niches or improve the efficiency to grow under the conditions of the existing niche. This review highlights differences in the TCS content between Staphylococcus aureus and Staphylococcus saprophyticus as a case study to exemplify how the ability to sense and respond to the environment is relevant for bacterial capacity to colonize and survive in/on different body surfaces.
AB - Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. Differences in the content of two-component systems are related with the capacity of the bacteria to colonize different niches or improve the efficiency to grow under the conditions of the existing niche. This review highlights differences in the TCS content between Staphylococcus aureus and Staphylococcus saprophyticus as a case study to exemplify how the ability to sense and respond to the environment is relevant for bacterial capacity to colonize and survive in/on different body surfaces.
U2 - 10.1016/j.mib.2020.02.004
DO - 10.1016/j.mib.2020.02.004
M3 - Review article
SN - 1369-5274
VL - 55
SP - 40
EP - 47
JO - Current Opinion in Microbiology
JF - Current Opinion in Microbiology
ER -