Abstract
Control of boronic acid speciation is presented as a strategy to achieve nucleophile chemoselectivity in the Suzuki-Miyaura reaction. Combined with simultaneous control of oxidative addition and transmetallation, this enables chemoselective formation of two C-C bonds in a single operation, providing a method for the rapid preparation of highly functionalized carbogenic frameworks.
| Original language | English |
|---|---|
| Pages (from-to) | 9976-9979 |
| Number of pages | 4 |
| Journal | Angewandte Chemie International Edition |
| Volume | 54 |
| Issue number | 34 |
| Early online date | 1 Jul 2015 |
| DOIs | |
| Publication status | Published - 17 Aug 2015 |
Keywords
- Boron
- Chemoselectivity
- Cross-coupling
- Palladium
- Speciation
Fingerprint
Dive into the research topics of 'Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control'. Together they form a unique fingerprint.Profiles
-
Allan Watson
- School of Chemistry - Deputy Head of School, Professor of Homogeneous Catalysis
Person: Academic
Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver