Abstract
Control of boronic acid speciation is presented as a strategy to achieve nucleophile chemoselectivity in the Suzuki-Miyaura reaction. Combined with simultaneous control of oxidative addition and transmetallation, this enables chemoselective formation of two C-C bonds in a single operation, providing a method for the rapid preparation of highly functionalized carbogenic frameworks.
Original language | English |
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Pages (from-to) | 9976-9979 |
Number of pages | 4 |
Journal | Angewandte Chemie International Edition |
Volume | 54 |
Issue number | 34 |
Early online date | 1 Jul 2015 |
DOIs | |
Publication status | Published - 17 Aug 2015 |
Keywords
- Boron
- Chemoselectivity
- Cross-coupling
- Palladium
- Speciation
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Dive into the research topics of 'Tandem chemoselective Suzuki-Miyaura cross-coupling enabled by nucleophile speciation control'. Together they form a unique fingerprint.Profiles
-
Allan John Bell Watson
- School of Chemistry - Professor of Homogeneous Catalysis
- Sir James Mackenzie Institute for Early Diagnosis
Person: Academic