Tackling polypharmacy: a multi-source decision support system

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Managing the use of multiple medicines, also known as polypharmacy, is a challenge for physicians, pharmacists and patients alike, and is a particular concern for patients with multiple chronic conditions (aka multimorbidity). Patients with multimorbidity are often required to take a considerable number of medications for their different ongoing conditions, and managing/revising these medications effectively is a challenge. There is a need to periodically rearrange drugs taking into account patient’s preferences and avoiding adverse drug reactions. We present an incremental, constraint solver based framework for a clinical decision support system that makes it possible to check drug prescriptions using information from multiple sources, including a constraint database and patient records. We illustrate how it can be used to manage clinical conditions while reducing polypharmacy problems and undesired side effects in a patient-centric approach.
Original languageEnglish
Title of host publicationDigital Personalized Health and Medicine
Subtitle of host publicationProceedings of MIE 2020
EditorsLouise Pape-Haugaard, Christian Lovis, Inge Corte Madsen, Patrick Weber, Per Hostrup Nielsen, Philip Scott
PublisherIOS Press
Pages688 - 692
Number of pages5
ISBN (Electronic)9781643680835
ISBN (Print)9781643680828
Publication statusPublished - 1 Jun 2020
Event30th Medical Informatics Europe conference (MIE) - Geneva International Conference Center, Geneva, Switzerland
Duration: 28 Apr 20201 May 2020
Conference number: 30

Publication series

NameStudies in Health Technology and Informatics
PublisherIOS Press
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365


Conference30th Medical Informatics Europe conference (MIE)
Abbreviated titleMIE
Internet address


  • Polypharmacy
  • Multimorbidity
  • Constraint solvers
  • Clinical decision support systems


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