Systematic review of the efficacy and safety of using mesh in surgery for uterine or vaginal vault prolapse

Xueli Jia; Cathryn Glazener; Graham Mowatt; David Jenkinson; Cynthia Fraser; Christine Bain; Jennifer Burr

doi:10.1007/s00192-010-1156-7

Systematic review of the efficacy and safety of using mesh in surgery for uterine or vaginal vault prolapse

Xueli Jia, Cathryn Glazener, Graham Mowatt, David Jenkinson, Cynthia Fraser, Christine Bain, Jennifer Burr

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Introduction and hypothesis The aim of this study is to estimate efficacy and safety of mesh in surgery for uterine or vault prolapse

Methods Seventeen electronic databases were searched for relevant studies that were published from 1980 onwards

Results Fifty-four studies involving 7,054 women were included. For sacrocolpopexy (average follow-up 23 months), the risk of clinical recurrence ranged from 0% to 6%, persistent symptoms ranged from 3% to 31% and mesh erosion from 0% to 12%. For infracoccygeal sacropexy (average follow-up 13 months), the risk of clinical recurrence ranged from 0% to 25%, persistent symptoms from 2% to 21% and mesh erosion 0% to 21%. Limited evidence was available for sacrocolpopenneopexy and uterine suspension sling to draw reliable estimates

Conclusions Sacrocolpopexy was associated with a low risk of recurrence but with a relatively high risk of mesh erosion Ranges of estimates for outcomes for other mesh techniques were wide

Original language	English
Pages (from-to)	1413-1431
Number of pages	19
Journal	International Urogynecology Journal
Volume	21
Issue number	11
DOIs	https://doi.org/10.1007/s00192-010-1156-7
Publication status	Published - Nov 2010

Keywords

Efficacy
Mesh
Mesh erosion
NICE
Pelvic organ prolapsed
Safety
Systematic review
ABDOMINAL SACRAL COLPOPEXY
POSTERIOR INTRAVAGINAL SLINGPLASTY
PELVIC ORGAN PROLAPSE
TERM-FOLLOW-UP
SYNTHETIC MESH
INFRACOCCYGEAL SACROPEXY
UTEROVAGINAL PROLAPSE
SACROSPINOUS COLPOPEXY
GENITAL PROLAPSE
YOUNG-WOMEN

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title = "Systematic review of the efficacy and safety of using mesh in surgery for uterine or vaginal vault prolapse",

abstract = "Introduction and hypothesis The aim of this study is to estimate efficacy and safety of mesh in surgery for uterine or vault prolapseMethods Seventeen electronic databases were searched for relevant studies that were published from 1980 onwardsResults Fifty-four studies involving 7,054 women were included. For sacrocolpopexy (average follow-up 23 months), the risk of clinical recurrence ranged from 0% to 6%, persistent symptoms ranged from 3% to 31% and mesh erosion from 0% to 12%. For infracoccygeal sacropexy (average follow-up 13 months), the risk of clinical recurrence ranged from 0% to 25%, persistent symptoms from 2% to 21% and mesh erosion 0% to 21%. Limited evidence was available for sacrocolpopenneopexy and uterine suspension sling to draw reliable estimatesConclusions Sacrocolpopexy was associated with a low risk of recurrence but with a relatively high risk of mesh erosion Ranges of estimates for outcomes for other mesh techniques were wide",

keywords = "Efficacy, Mesh, Mesh erosion, NICE, Pelvic organ prolapsed, Safety, Systematic review, ABDOMINAL SACRAL COLPOPEXY, POSTERIOR INTRAVAGINAL SLINGPLASTY, PELVIC ORGAN PROLAPSE, TERM-FOLLOW-UP, SYNTHETIC MESH, INFRACOCCYGEAL SACROPEXY, UTEROVAGINAL PROLAPSE, SACROSPINOUS COLPOPEXY, GENITAL PROLAPSE, YOUNG-WOMEN",

author = "Xueli Jia and Cathryn Glazener and Graham Mowatt and David Jenkinson and Cynthia Fraser and Christine Bain and Jennifer Burr",

year = "2010",

month = nov,

doi = "10.1007/s00192-010-1156-7",

language = "English",

volume = "21",

pages = "1413--1431",

journal = "International Urogynecology Journal",

issn = "0937-3462",

publisher = "Springer",

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TY - JOUR

T1 - Systematic review of the efficacy and safety of using mesh in surgery for uterine or vaginal vault prolapse

AU - Jia, Xueli

AU - Glazener, Cathryn

AU - Mowatt, Graham

AU - Jenkinson, David

AU - Fraser, Cynthia

AU - Bain, Christine

AU - Burr, Jennifer

PY - 2010/11

Y1 - 2010/11

N2 - Introduction and hypothesis The aim of this study is to estimate efficacy and safety of mesh in surgery for uterine or vault prolapseMethods Seventeen electronic databases were searched for relevant studies that were published from 1980 onwardsResults Fifty-four studies involving 7,054 women were included. For sacrocolpopexy (average follow-up 23 months), the risk of clinical recurrence ranged from 0% to 6%, persistent symptoms ranged from 3% to 31% and mesh erosion from 0% to 12%. For infracoccygeal sacropexy (average follow-up 13 months), the risk of clinical recurrence ranged from 0% to 25%, persistent symptoms from 2% to 21% and mesh erosion 0% to 21%. Limited evidence was available for sacrocolpopenneopexy and uterine suspension sling to draw reliable estimatesConclusions Sacrocolpopexy was associated with a low risk of recurrence but with a relatively high risk of mesh erosion Ranges of estimates for outcomes for other mesh techniques were wide

AB - Introduction and hypothesis The aim of this study is to estimate efficacy and safety of mesh in surgery for uterine or vault prolapseMethods Seventeen electronic databases were searched for relevant studies that were published from 1980 onwardsResults Fifty-four studies involving 7,054 women were included. For sacrocolpopexy (average follow-up 23 months), the risk of clinical recurrence ranged from 0% to 6%, persistent symptoms ranged from 3% to 31% and mesh erosion from 0% to 12%. For infracoccygeal sacropexy (average follow-up 13 months), the risk of clinical recurrence ranged from 0% to 25%, persistent symptoms from 2% to 21% and mesh erosion 0% to 21%. Limited evidence was available for sacrocolpopenneopexy and uterine suspension sling to draw reliable estimatesConclusions Sacrocolpopexy was associated with a low risk of recurrence but with a relatively high risk of mesh erosion Ranges of estimates for outcomes for other mesh techniques were wide

KW - Efficacy

KW - Mesh

KW - Mesh erosion

KW - NICE

KW - Pelvic organ prolapsed

KW - Safety

KW - Systematic review

KW - ABDOMINAL SACRAL COLPOPEXY

KW - POSTERIOR INTRAVAGINAL SLINGPLASTY

KW - PELVIC ORGAN PROLAPSE

KW - TERM-FOLLOW-UP

KW - SYNTHETIC MESH

KW - INFRACOCCYGEAL SACROPEXY

KW - UTEROVAGINAL PROLAPSE

KW - SACROSPINOUS COLPOPEXY

KW - GENITAL PROLAPSE

KW - YOUNG-WOMEN

UR - http://hdl.handle.net/2164/2070

U2 - 10.1007/s00192-010-1156-7

DO - 10.1007/s00192-010-1156-7

M3 - Review article

SN - 0937-3462

VL - 21

SP - 1413

EP - 1431

JO - International Urogynecology Journal

JF - International Urogynecology Journal

IS - 11

ER -

Systematic review of the efficacy and safety of using mesh in surgery for uterine or vaginal vault prolapse

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