Synthesis of (diarylmethyl)amines using Ni-catalyzed arylation of C(sp3)-H bonds

Jose Antonio Fernandez Salas, Enrico Marelli, Steven Patrick Nolan

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)
2 Downloads (Pure)


The first nickel catalyzed deprotonative cross coupling between C(sp3)-H bonds and aryl chlorides is reported, allowing the challenging arylation of benzylimines in the absence of directing group or stoichiometric metal activation. This methodology represents a convenient access to the (diarylmethyl)amine moiety, which is widespread in pharmaceutically relevant compounds.

Original languageEnglish
Pages (from-to)4973-4977
Number of pages5
JournalJournal of Polymer Science Part A: Polymer Chemistry
Issue number8
Early online date12 Jun 2015
Publication statusPublished - 1 Aug 2015


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