Projects per year
Abstract
A Rh-catalyzed [2+2+2] cycloaddition approach for the synthesis of BMIDA-functionalized arenes is reported. The developed method overcomes the long-standing reactivity problems associated with internal alkynes and allows access to highly functionalized borylated benzene scaffolds. The method is broadly functional group tolerant and generally high yielding. The utility of the products is demonstrated through elaboration of the BMIDA motif, and in the synthesis of fused heterocycles via intramolecular Chan–Lam etherification and amination. The dominance of sterically controlled reactivity is described.
Original language | English |
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Pages (from-to) | 7759-7762 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 59 |
Issue number | 50 |
Early online date | 26 May 2023 |
DOIs | |
Publication status | Published - 25 Jun 2023 |
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Dive into the research topics of 'Synthesis of complex aryl MIDA boronates by Rh-catalyzed [2+2+2] cycloaddition'. Together they form a unique fingerprint.Projects
- 1 Finished
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A biochemical boron tagging stategy: A biochemical boron tagging strategy for biomolecule visualisation and profiling
Watson, A. J. B. (PI)
1/09/22 → 31/08/24
Project: Fellowship
Datasets
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Dataset underpinning "Synthesis of complex aryl MIDA boronates by Rh-catalyzed [2+2+2] cycloaddition"
Watson, A. J. B. (Creator), University of St Andrews, 2 Jun 2023
DOI: 10.17630/b45cb8f3-7047-4839-b413-df49ab7f3e7d
Dataset
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