SYNTHESIS AND X-RAY CRYSTAL-STRUCTURE OF A NEW CHOLAPHANE WITH EXTERNALLY DIRECTED FUNCTIONALITY

A P DAVIS, M G ORCHARD, A M Z SLAWIN, D J WILLIAMS

Research output: Contribution to journalArticlepeer-review

Abstract

The 'cholaphane' 1 was synthesized in 26% overall yield from cholic acid and its structure determined by X-ray crystallography; the molecule adopts an open conformation and is able to surround two molecules of tetrahydrofuran.

Original languageEnglish
Pages (from-to)612-614
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number9
Publication statusPublished - 1 May 1991

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