Synthesis and single crystal structures of N-substituted benzamides and their chemoselective selenation/reduction derivatives

Guoxiong Hua; Cameron L. Carpenter-Warren; David B. Cordes; Alexandra M. Z. Slawin; J. Derek Woollins

doi:10.3390/molecules26082367

Synthesis and single crystal structures of N-substituted benzamides and their chemoselective selenation/reduction derivatives

Guoxiong Hua, Cameron L. Carpenter-Warren, David B. Cordes, Alexandra M. Z. Slawin, J. Derek Woollins

Research output: Contribution to journal › Article › peer-review

Abstract

A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl) benzoselenoamides in good yields. Five representative single crystal X-ray structures are discussed.

Original language	English
Article number	2367
Number of pages	10
Journal	Molecules
Volume	26
Issue number	8
DOIs	https://doi.org/10.3390/molecules26082367
Publication status	Published - 19 Apr 2021

Keywords

N-substituted benzamides
Woollins’ reagent
Selenation reagent
Reduction reagent
Single crystal X-ray structures

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10.3390/molecules26082367Licence: CC BY

Hua-2021-Synthesis-and-single-crystal-Molecules-26-02367
Copyright © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
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Cite this

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title = "Synthesis and single crystal structures of N-substituted benzamides and their chemoselective selenation/reduction derivatives",

abstract = "A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins{\textquoteright} reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl) benzoselenoamides in good yields. Five representative single crystal X-ray structures are discussed.",

keywords = "N-substituted benzamides, Woollins{\textquoteright} reagent, Selenation reagent, Reduction reagent, Single crystal X-ray structures",

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T1 - Synthesis and single crystal structures of N-substituted benzamides and their chemoselective selenation/reduction derivatives

AU - Hua, Guoxiong

AU - Carpenter-Warren, Cameron L.

AU - Cordes, David B.

AU - Slawin, Alexandra M. Z.

AU - Woollins, J. Derek

PY - 2021/4/19

Y1 - 2021/4/19

N2 - A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl) benzoselenoamides in good yields. Five representative single crystal X-ray structures are discussed.

AB - A series of N-aryl-N-(2-oxo-2-arylethyl) benzamides and cinnamides has been prepared. The reaction of the benzamides with Woollins’ reagent, a highly efficient chemoselective selenation/reduction reagent, gave the corresponding N-aryl-N-(arylenethyl) benzoselenoamides in good yields. Five representative single crystal X-ray structures are discussed.

KW - N-substituted benzamides

KW - Woollins’ reagent

KW - Selenation reagent

KW - Reduction reagent

KW - Single crystal X-ray structures

UR - https://www.mdpi.com/journal/molecules/special_issues/Alexandra_Slawin

UR - https://www.mdpi.com/1420-3049/26/8/2367

U2 - 10.3390/molecules26082367

DO - 10.3390/molecules26082367

M3 - Article

SN - 1420-3049

VL - 26

JO - Molecules

JF - Molecules

IS - 8

M1 - 2367

ER -

Synthesis and single crystal structures of N-substituted benzamides and their chemoselective selenation/reduction derivatives

Abstract

Keywords

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CCDC 2071413 - 2071417: Experimental Crystal Structure Determination

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Synthesis and single crystal structures of N-substituted benzamides and their chemoselective selenation/reduction derivatives

Abstract

Keywords

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Datasets

CCDC 2071413 - 2071417: Experimental Crystal Structure Determination

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