Abstract
The 8-chlorobicyclo[3.2.1]oct-6-ene 3 has been prepared by a [3+2] cycloaddition route, and converted to the bicyclic alpha -methylene ketones 6 and 8-12. some of which showed cytotoxic properties. (C) 2001 Elsevier Science Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 2729-2731 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 42 |
Publication status | Published - 2 Apr 2001 |
Keywords
- [3+2] cycloaddition
- Hg(II) mediated hydrolysis
- alkynyl and vinyl sulphide
- bicyclo[3.2.1]octane alpha-methylene ketones
- cytotoxicity
- TERRECYCLIC ACID-A
- ASPERGILLUS-TERREUS
- PROSTANOIDS