TY - JOUR
T1 - Susceptibility of pseudomonas pseudomallei to new β-lactam and aminoglycoside antibiotics
AU - Mceniry, David W.
AU - Gillespie, Stephen H.
AU - Felmingham, David
PY - 1988/2
Y1 - 1988/2
N2 - Pseudomonas pseudomallei is resistant to many antimicrobial agents. We determined the susceptibility to twelve β-lactams and six aminoglycosides of twelve isolates of P. pseudomallei. Imipenem (MIC range 0·5-1·0 mg/l; MIC90 10 mg/l), ceftazidime (MIC range 1-8 mg/l; MIC90 8·0 mg/l), amoxycillin/clavulanate (MIC range 4-8 mg/l; MIC90 8·0 mg/l), piperacillin (MIC range 4-16 mg/l; MIC90 8·0 mg/l), and carumonam (MIC range 4-;16 mg/l; MIC90 8·0 mg/l) were the most active. Aminoglycosides were relatively inactive, for example, gentamicin (MIC range 16-64 mg/l; MIC90 64 mg/l), netilmicin (MIC range 16-128 mg/l; MIC90 128 mg/l) and amikacin (MIC range 32-64 mg/l; MIC90 64 mg/l).
AB - Pseudomonas pseudomallei is resistant to many antimicrobial agents. We determined the susceptibility to twelve β-lactams and six aminoglycosides of twelve isolates of P. pseudomallei. Imipenem (MIC range 0·5-1·0 mg/l; MIC90 10 mg/l), ceftazidime (MIC range 1-8 mg/l; MIC90 8·0 mg/l), amoxycillin/clavulanate (MIC range 4-8 mg/l; MIC90 8·0 mg/l), piperacillin (MIC range 4-16 mg/l; MIC90 8·0 mg/l), and carumonam (MIC range 4-;16 mg/l; MIC90 8·0 mg/l) were the most active. Aminoglycosides were relatively inactive, for example, gentamicin (MIC range 16-64 mg/l; MIC90 64 mg/l), netilmicin (MIC range 16-128 mg/l; MIC90 128 mg/l) and amikacin (MIC range 32-64 mg/l; MIC90 64 mg/l).
UR - http://www.scopus.com/inward/record.url?scp=0023884596&partnerID=8YFLogxK
U2 - 10.1093/jac/21.2.171
DO - 10.1093/jac/21.2.171
M3 - Article
C2 - 3162898
AN - SCOPUS:0023884596
SN - 0305-7453
VL - 21
SP - 171
EP - 175
JO - Journal of Antimicrobial Chemotherapy
JF - Journal of Antimicrobial Chemotherapy
IS - 2
ER -
