SuperQuat, (S)-4-benzyl-5,5-dimethyl-oxazolidin-2-one for the asymmetric synthesis of α-substituted-aldehydes

Steven D. Bull, Stephen G. Davies*, Rebecca L. Nicholson, Hitesh J. Sanganee, Andrew D. Smith

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Reduction of α-substituted-(S)-N-acyl-4-benzyl-5,5-dimethyl-oxazolidin-2-ones with DIBAL-H in CH2Cl2 affords α-substituted aldehydes with no loss of stereochemical integrity at their α-centre. Copyright (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)3475-3479
Number of pages5
JournalTetrahedron Asymmetry
Volume11
Issue number17
DOIs
Publication statusPublished - 8 Sept 2000

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