Structure, conformation, and mechanism in the membrane transport of alkali metal ions by ionophoric antibiotics

F G Riddell

Research output: Contribution to journalReview articlepeer-review

55 Citations (Scopus)

Abstract

Recent progress in studies of the mechanism of transport of alkali metal ions by ionophoric antibiotics and the structures of alkali metal salts of the ionophores monensin and narasin is reviewed. The structures obtained from 2D NMR experiments in solution provide considerable insights into the mechanisms of transport. (C) 2002 Wiley-Liss, Inc.

Original languageEnglish
Pages (from-to)121-125
Number of pages5
JournalChirality
Volume14
Publication statusPublished - Feb 2002

Keywords

  • ionophoric antibiotic
  • membrane transport
  • NMR spectroscopy
  • MONENSIN-MEDIATED TRANSPORT
  • MOLECULAR-STRUCTURE
  • NMR-SPECTROSCOPY
  • SODIUM COMPLEX
  • SOLID-STATE
  • K+ IONS
  • SALINOMYCIN
  • NA-23-NMR
  • K-39-NMR
  • CRYSTAL

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