First microwave accelerated Hiyama couplings: clean cross-coupling of aryl chlorides within minutes.

Matthew L Clarke

doi:10.1002/adsc.200404196

First microwave accelerated Hiyama couplings: clean cross-coupling of aryl chlorides within minutes.

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Abstract

The first microwave-accelerated Hiyama cross-coupling reactions are reported. The reactions of aryl bromides and activated aryl chlorides with PhSi(OMe)(3) [or C2H3Si(OMe)(3)] are complete within minutes using a modified catalyst system that can be prepared from commercially available reagents in situ. The microwave-accelerated reactions proceed under relatively mild conditions (110-115degreesC).

Original language	English
Pages (from-to)	303
Number of pages	303
Journal	Advanced Synthesis & Catalysis
Volume	347
DOIs	https://doi.org/10.1002/adsc.200404196
Publication status	Published - Feb 2005

Keywords

cross-coupling
homogeneous catalysis
microwave heating
palladium
phosphane ligands
ORGANIC HALIDES
REAGENTS
CATALYST
BROMIDES
PHOSPHINES
COMPLEXES
AMINATION
NEGISHI
SYSTEM

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title = "First microwave accelerated Hiyama couplings: clean cross-coupling of aryl chlorides within minutes.",

abstract = "The first microwave-accelerated Hiyama cross-coupling reactions are reported. The reactions of aryl bromides and activated aryl chlorides with PhSi(OMe)(3) [or C2H3Si(OMe)(3)] are complete within minutes using a modified catalyst system that can be prepared from commercially available reagents in situ. The microwave-accelerated reactions proceed under relatively mild conditions (110-115degreesC).",

keywords = "cross-coupling, homogeneous catalysis, microwave heating, palladium, phosphane ligands, ORGANIC HALIDES, REAGENTS, CATALYST, BROMIDES, PHOSPHINES, COMPLEXES, AMINATION, NEGISHI, SYSTEM",

author = "Clarke, \{Matthew L\}",

year = "2005",

month = feb,

doi = "10.1002/adsc.200404196",

language = "English",

volume = "347",

pages = "303",

journal = "Advanced Synthesis \& Catalysis",

issn = "1615-4150",

publisher = "Wiley-VCH, Weinheim",

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T1 - First microwave accelerated Hiyama couplings: clean cross-coupling of aryl chlorides within minutes.

AU - Clarke, Matthew L

PY - 2005/2

Y1 - 2005/2

N2 - The first microwave-accelerated Hiyama cross-coupling reactions are reported. The reactions of aryl bromides and activated aryl chlorides with PhSi(OMe)(3) [or C2H3Si(OMe)(3)] are complete within minutes using a modified catalyst system that can be prepared from commercially available reagents in situ. The microwave-accelerated reactions proceed under relatively mild conditions (110-115degreesC).

AB - The first microwave-accelerated Hiyama cross-coupling reactions are reported. The reactions of aryl bromides and activated aryl chlorides with PhSi(OMe)(3) [or C2H3Si(OMe)(3)] are complete within minutes using a modified catalyst system that can be prepared from commercially available reagents in situ. The microwave-accelerated reactions proceed under relatively mild conditions (110-115degreesC).

KW - cross-coupling

KW - homogeneous catalysis

KW - microwave heating

KW - palladium

KW - phosphane ligands

KW - ORGANIC HALIDES

KW - REAGENTS

KW - CATALYST

KW - BROMIDES

KW - PHOSPHINES

KW - COMPLEXES

KW - AMINATION

KW - NEGISHI

KW - SYSTEM

UR - https://www.scopus.com/pages/publications/15044357725

UR - http://www3.interscience.wiley.com/cgi-bin/fulltext/109924720/PDFSTART

U2 - 10.1002/adsc.200404196

DO - 10.1002/adsc.200404196

M3 - Article

SN - 1615-4150

VL - 347

SP - 303

JO - Advanced Synthesis & Catalysis

JF - Advanced Synthesis & Catalysis

ER -

First microwave accelerated Hiyama couplings: clean cross-coupling of aryl chlorides within minutes.

Abstract

Keywords

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