Stitching organelles: organization and function of specialized membrane contact sites in plants

Jessica Pérez-Sancho, Jens Tilsner, A. Lacey Samuels, Miguel A. Botella, Emmanuelle M. Bayer, Abel Rosado

Research output: Contribution to journalReview articlepeer-review

86 Citations (Scopus)
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Abstract

The coordination of multiple metabolic activities in plants relies on an interorganelle communication network established through membrane contact sites (MCS). The MCS are maintained in transient or durable configurations by tethering structures which keep the two membranes in close proximity, and create chemical microdomains that allow localized and targeted exchange of small molecules and possibly proteins. The past few years have witnessed a dramatic increase in our understanding of the structural and molecular organization of plant interorganelle MCS, and their crucial roles in plant specialized functions including stress responses, cell to cell communication, and lipid transport. In this review we summarize recent advances in understanding the molecular components, structural organization, and functions of different plant-specific MCS architectures.
Original languageEnglish
Pages (from-to)705-717
JournalTrends in Cell Biology
Volume26
Issue number9
Early online date15 Jun 2016
DOIs
Publication statusPublished - Sept 2016

Keywords

  • Plasmodesmata
  • PLAMs
  • Stress-inducible MCS
  • Tethers
  • SYT
  • VAP27

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