Stitching organelles: organization and function of specialized membrane contact sites in plants

Jessica Pérez-Sancho; Jens Tilsner; A. Lacey Samuels; Miguel A. Botella; Emmanuelle M. Bayer; Abel Rosado

doi:10.1016/j.tcb.2016.05.007

Stitching organelles: organization and function of specialized membrane contact sites in plants

Jessica Pérez-Sancho, Jens Tilsner, A. Lacey Samuels, Miguel A. Botella, Emmanuelle M. Bayer, Abel Rosado

Research output: Contribution to journal › Review article › peer-review

Abstract

The coordination of multiple metabolic activities in plants relies on an interorganelle communication network established through membrane contact sites (MCS). The MCS are maintained in transient or durable configurations by tethering structures which keep the two membranes in close proximity, and create chemical microdomains that allow localized and targeted exchange of small molecules and possibly proteins. The past few years have witnessed a dramatic increase in our understanding of the structural and molecular organization of plant interorganelle MCS, and their crucial roles in plant specialized functions including stress responses, cell to cell communication, and lipid transport. In this review we summarize recent advances in understanding the molecular components, structural organization, and functions of different plant-specific MCS architectures.

Original language	English
Pages (from-to)	705-717
Journal	Trends in Cell Biology
Volume	26
Issue number	9
Early online date	15 Jun 2016
DOIs	https://doi.org/10.1016/j.tcb.2016.05.007
Publication status	Published - Sept 2016

Keywords

Plasmodesmata
PLAMs
Stress-inducible MCS
Tethers
SYT
VAP27

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10.1016/j.tcb.2016.05.007

Tilsner_2016_TCB_Stitching_AAM
© 2016 Elsevier Ltd. All rights reserved. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1016/j.tcb.2016.05.007
Accepted author manuscript, 2.23 MB

Cite this

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title = "Stitching organelles: organization and function of specialized membrane contact sites in plants",

abstract = "The coordination of multiple metabolic activities in plants relies on an interorganelle communication network established through membrane contact sites (MCS). The MCS are maintained in transient or durable configurations by tethering structures which keep the two membranes in close proximity, and create chemical microdomains that allow localized and targeted exchange of small molecules and possibly proteins. The past few years have witnessed a dramatic increase in our understanding of the structural and molecular organization of plant interorganelle MCS, and their crucial roles in plant specialized functions including stress responses, cell to cell communication, and lipid transport. In this review we summarize recent advances in understanding the molecular components, structural organization, and functions of different plant-specific MCS architectures.",

keywords = "Plasmodesmata, PLAMs, Stress-inducible MCS, Tethers, SYT, VAP27",

author = "Jessica P{\'e}rez-Sancho and Jens Tilsner and Samuels, {A. Lacey} and Botella, {Miguel A.} and Bayer, {Emmanuelle M.} and Abel Rosado",

note = "This work was supported by the Canada Research Chairs Program (to A.R.), two Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Grants (to A.R. and L.S.), a Research Training Fellowship from the Ministerio de Econom{\'i}a y Competitividad (FPI-BES 2012-052324 to J.P-S.), the Ministerio de Ciencia e Innovaci{\'o}n (co-financed by the European Regional Development Fund; grant BIO2014-55380-R to M.A.B.), the UK Biotechnology and Biological Sciences Research Council (BBSRC grant BB/M007200/1 to J.T.), and the French National Agency for Research (grant ANR-14-CE19-0006-01 to E.B.).",

year = "2016",

month = sep,

doi = "10.1016/j.tcb.2016.05.007",

language = "English",

volume = "26",

pages = "705--717",

journal = "Trends in Cell Biology",

issn = "0962-8924",

publisher = "Elsevier",

number = "9",

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T2 - organization and function of specialized membrane contact sites in plants

AU - Pérez-Sancho, Jessica

AU - Tilsner, Jens

AU - Samuels, A. Lacey

AU - Botella, Miguel A.

AU - Bayer, Emmanuelle M.

AU - Rosado, Abel

N1 - This work was supported by the Canada Research Chairs Program (to A.R.), two Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Grants (to A.R. and L.S.), a Research Training Fellowship from the Ministerio de Economía y Competitividad (FPI-BES 2012-052324 to J.P-S.), the Ministerio de Ciencia e Innovación (co-financed by the European Regional Development Fund; grant BIO2014-55380-R to M.A.B.), the UK Biotechnology and Biological Sciences Research Council (BBSRC grant BB/M007200/1 to J.T.), and the French National Agency for Research (grant ANR-14-CE19-0006-01 to E.B.).

PY - 2016/9

Y1 - 2016/9

N2 - The coordination of multiple metabolic activities in plants relies on an interorganelle communication network established through membrane contact sites (MCS). The MCS are maintained in transient or durable configurations by tethering structures which keep the two membranes in close proximity, and create chemical microdomains that allow localized and targeted exchange of small molecules and possibly proteins. The past few years have witnessed a dramatic increase in our understanding of the structural and molecular organization of plant interorganelle MCS, and their crucial roles in plant specialized functions including stress responses, cell to cell communication, and lipid transport. In this review we summarize recent advances in understanding the molecular components, structural organization, and functions of different plant-specific MCS architectures.

AB - The coordination of multiple metabolic activities in plants relies on an interorganelle communication network established through membrane contact sites (MCS). The MCS are maintained in transient or durable configurations by tethering structures which keep the two membranes in close proximity, and create chemical microdomains that allow localized and targeted exchange of small molecules and possibly proteins. The past few years have witnessed a dramatic increase in our understanding of the structural and molecular organization of plant interorganelle MCS, and their crucial roles in plant specialized functions including stress responses, cell to cell communication, and lipid transport. In this review we summarize recent advances in understanding the molecular components, structural organization, and functions of different plant-specific MCS architectures.

KW - Plasmodesmata

KW - PLAMs

KW - Stress-inducible MCS

KW - Tethers

KW - SYT

KW - VAP27

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DO - 10.1016/j.tcb.2016.05.007

M3 - Review article

SN - 0962-8924

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SP - 705

EP - 717

JO - Trends in Cell Biology

JF - Trends in Cell Biology

IS - 9

ER -

Stitching organelles: organization and function of specialized membrane contact sites in plants

Abstract

Keywords

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lipid catabolism: Investigating the typanosomatid lysosome and its role in lipid catabolism.

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Stitching organelles: organization and function of specialized membrane contact sites in plants

Abstract

Keywords

Access to Document

Other files and links

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Projects

lipid catabolism: Investigating the typanosomatid lysosome and its role in lipid catabolism.

Push on through to the other side: Push on through to the other side- molecular basis of viral cell-to-cell movement in plants

Cite this