Solid-phase synthesis and catalytic screening of polystyrene supported diphosphines

M. C. Samuels; F. J. L. Heutz; A. Grabulosa; P. C. J. Kamer

doi:10.1007/s11244-016-0700-1

Solid-phase synthesis and catalytic screening of polystyrene supported diphosphines

M. C. Samuels, F. J. L. Heutz, A. Grabulosa, P. C. J. Kamer

Research output: Contribution to journal › Article › peer-review

Abstract

An efficient modular method towards the synthesis of a library of polystyrene supported diphosphine ligands by combining solid-phase synthesis with rational ligand design has been developed. These supported ligands, obtained in quantitative yield, were efficiently and effectively screened in Rh-catalysed asymmetric hydrogenation of several benchmark substrates.

Original language	English
Pages (from-to)	1793-1799
Number of pages	7
Journal	Topics in Catalysis
Volume	59
Issue number	19
Early online date	25 Aug 2016
DOIs	https://doi.org/10.1007/s11244-016-0700-1
Publication status	Published - Dec 2016

Keywords

Solid-phase synthesis
Asymmetric catalysis
Combinatorial chemistry
P ligands
Catalyst immobilisation

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10.1007/s11244-016-0700-1Licence: CC BY

Kamer_2016_TiC_Solid_CCBY-FinalPublishedVersion
© The Authors 2016. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
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Cite this

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abstract = "An efficient modular method towards the synthesis of a library of polystyrene supported diphosphine ligands by combining solid-phase synthesis with rational ligand design has been developed. These supported ligands, obtained in quantitative yield, were efficiently and effectively screened in Rh-catalysed asymmetric hydrogenation of several benchmark substrates.",

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author = "Samuels, {M. C.} and Heutz, {F. J. L.} and A. Grabulosa and Kamer, {P. C. J.}",

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AU - Grabulosa, A.

AU - Kamer, P. C. J.

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KW - Solid-phase synthesis

KW - Asymmetric catalysis

KW - Combinatorial chemistry

KW - P ligands

KW - Catalyst immobilisation

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Solid-phase synthesis and catalytic screening of polystyrene supported diphosphines

Abstract

Keywords

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Marie Curie SusPhos: A European Trainging Network for Sustainable Phosphorus Chemistry

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Solid-phase synthesis and catalytic screening of polystyrene supported diphosphines

Abstract

Keywords

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Projects

Marie Curie SusPhos: A European Trainging Network for Sustainable Phosphorus Chemistry

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