Simple (imidazol-2-ylidene)-Pd-acetate complexes as effective precatalysts for sterically hindered Suzuki-Miyaura couplings

R Singh; MS Viciu; N Kramareva; O Navarro; Steven Patrick Nolan

doi:10.1021/ol050472o

Simple (imidazol-2-ylidene)-Pd-acetate complexes as effective precatalysts for sterically hindered Suzuki-Miyaura couplings

R Singh, MS Viciu, N Kramareva, O Navarro, Steven Patrick Nolan

Research output: Contribution to journal › Article › peer-review

Abstract

A simplified synthesis of N-heterocyclic carbene (NHC)Pd-carboxylate complexes and their activity in Suzuki-Miyaura cross-coupling reactions are described. Coupling of sterically hindered aryl and activated alkyl chlorides bearing 6-hydrogens has been successfully achieved.

Original language	English
Pages (from-to)	1829-1832
Number of pages	4
Journal	Organic Letters
Volume	7
Issue number	9
DOIs	https://doi.org/10.1021/ol050472o
Publication status	Published - 28 Apr 2005

Keywords

CATALYZED AEROBIC OXIDATION
CROSS-COUPLINGS
ROOM-TEMPERATURE
ARYL CHLORIDES
ALKYL BROMIDES
ORGANOBORON COMPOUNDS
PHENYLBORONIC ACID
ARYLBORONIC ACIDS
MILD CONDITIONS
BOND FORMATION

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title = "Simple (imidazol-2-ylidene)-Pd-acetate complexes as effective precatalysts for sterically hindered Suzuki-Miyaura couplings",

abstract = "A simplified synthesis of N-heterocyclic carbene (NHC)Pd-carboxylate complexes and their activity in Suzuki-Miyaura cross-coupling reactions are described. Coupling of sterically hindered aryl and activated alkyl chlorides bearing 6-hydrogens has been successfully achieved.",

keywords = "CATALYZED AEROBIC OXIDATION, CROSS-COUPLINGS, ROOM-TEMPERATURE, ARYL CHLORIDES, ALKYL BROMIDES, ORGANOBORON COMPOUNDS, PHENYLBORONIC ACID, ARYLBORONIC ACIDS, MILD CONDITIONS, BOND FORMATION",

author = "R Singh and MS Viciu and N Kramareva and O Navarro and Nolan, {Steven Patrick}",

year = "2005",

month = apr,

day = "28",

doi = "10.1021/ol050472o",

language = "English",

volume = "7",

pages = "1829--1832",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society (ACS)",

number = "9",

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TY - JOUR

T1 - Simple (imidazol-2-ylidene)-Pd-acetate complexes as effective precatalysts for sterically hindered Suzuki-Miyaura couplings

AU - Singh, R

AU - Viciu, MS

AU - Kramareva, N

AU - Navarro, O

AU - Nolan, Steven Patrick

PY - 2005/4/28

Y1 - 2005/4/28

N2 - A simplified synthesis of N-heterocyclic carbene (NHC)Pd-carboxylate complexes and their activity in Suzuki-Miyaura cross-coupling reactions are described. Coupling of sterically hindered aryl and activated alkyl chlorides bearing 6-hydrogens has been successfully achieved.

AB - A simplified synthesis of N-heterocyclic carbene (NHC)Pd-carboxylate complexes and their activity in Suzuki-Miyaura cross-coupling reactions are described. Coupling of sterically hindered aryl and activated alkyl chlorides bearing 6-hydrogens has been successfully achieved.

KW - CATALYZED AEROBIC OXIDATION

KW - CROSS-COUPLINGS

KW - ROOM-TEMPERATURE

KW - ARYL CHLORIDES

KW - ALKYL BROMIDES

KW - ORGANOBORON COMPOUNDS

KW - PHENYLBORONIC ACID

KW - ARYLBORONIC ACIDS

KW - MILD CONDITIONS

KW - BOND FORMATION

UR - http://www.scopus.com/inward/record.url?scp=18844421600&partnerID=8YFLogxK

U2 - 10.1021/ol050472o

DO - 10.1021/ol050472o

M3 - Article

SN - 1523-7060

VL - 7

SP - 1829

EP - 1832

JO - Organic Letters

JF - Organic Letters

IS - 9

ER -

Simple (imidazol-2-ylidene)-Pd-acetate complexes as effective precatalysts for sterically hindered Suzuki-Miyaura couplings

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Keywords

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