Shining a light on the future of biophotonics

Francesco Baldini; Kishan Dholakia; Paul French; Orlando Guntinas‐Lichius; Achim Kohler; Werner Mäntele; Laura Marcu; Ronald Sroka; Siva Umapathy; Juergen Popp

doi:10.1002/jbio.202500148

Shining a light on the future of biophotonics

Francesco Baldini
, Kishan Dholakia
, Paul French
, Orlando Guntinas‐Lichius
, Achim Kohler
, Werner Mäntele
, Laura Marcu
, Ronald Sroka
, Siva Umapathy
, Juergen Popp^*

^*Corresponding author for this work

School of Physics and Astronomy

Research output: Contribution to journal › Article › peer-review

Abstract

ABSTRACTBiophotonics—the interdisciplinary fusion of light‐based technologies with biology and medicine—is rapidly transforming research, diagnostics, and therapy across various domains. This white paper, developed in conjunction with the International Congress on Biophotonics 2024, offers a comprehensive overview of the current landscape and future potential of biophotonics. It discusses core technologies such as bioimaging, biosensing, and photonic‐based therapies, while highlighting novel applications in oncology, infectious diseases, neurology, cardiovascular health, agriculture, food safety, and environmental monitoring. The document also explores key enablers, including artificial intelligence, novel materials, and quantum biophotonics, along with critical challenges related to standardization, regulation, and clinical translation. A SWOT analysis and recommendations are provided to guide future research, commercialization, and interdisciplinary collaboration, underscoring biophotonics as a cornerstone of next‐generation precision medicine and the One Health approach.

Original language	English
Article number	e202500148
Journal	Journal of Biophotonics
Volume	18
Issue number	7
Early online date	14 May 2025
DOIs	https://doi.org/10.1002/jbio.202500148
Publication status	Published - 10 Jul 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Artificial intelligence
Bioimaging
Biophotonics
Biosensing
Clinical translation
Laser medicine
One health
Optical health technologies
Photonic therapy

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10.1002/jbio.202500148Licence: CC BY

Baldini_2025_JoB_Shining-a-light-future_CC
Copyright © 2025 The Author(s). Journal of Biophotonics published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Final published version, 1.28 MBLicence: CC BY

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title = "Shining a light on the future of biophotonics",

abstract = "ABSTRACTBiophotonics—the interdisciplinary fusion of light‐based technologies with biology and medicine—is rapidly transforming research, diagnostics, and therapy across various domains. This white paper, developed in conjunction with the International Congress on Biophotonics 2024, offers a comprehensive overview of the current landscape and future potential of biophotonics. It discusses core technologies such as bioimaging, biosensing, and photonic‐based therapies, while highlighting novel applications in oncology, infectious diseases, neurology, cardiovascular health, agriculture, food safety, and environmental monitoring. The document also explores key enablers, including artificial intelligence, novel materials, and quantum biophotonics, along with critical challenges related to standardization, regulation, and clinical translation. A SWOT analysis and recommendations are provided to guide future research, commercialization, and interdisciplinary collaboration, underscoring biophotonics as a cornerstone of next‐generation precision medicine and the One Health approach.",

keywords = "Artificial intelligence, Bioimaging, Biophotonics, Biosensing, Clinical translation, Laser medicine, One health, Optical health technologies, Photonic therapy",

author = "Francesco Baldini and Kishan Dholakia and Paul French and Orlando Guntinas‐Lichius and Achim Kohler and Werner M{\"a}ntele and Laura Marcu and Ronald Sroka and Siva Umapathy and Juergen Popp",

note = "Funding: Open Access funding enabled and organized by Projekt DEAL.",

year = "2025",

month = jul,

day = "10",

doi = "10.1002/jbio.202500148",

language = "English",

volume = "18",

journal = "Journal of Biophotonics",

issn = "1864-063X",

publisher = "Wiley-VCH, Weinheim",

number = "7",

}

TY - JOUR

T1 - Shining a light on the future of biophotonics

AU - Baldini, Francesco

AU - Dholakia, Kishan

AU - French, Paul

AU - Guntinas‐Lichius, Orlando

AU - Kohler, Achim

AU - Mäntele, Werner

AU - Marcu, Laura

AU - Sroka, Ronald

AU - Umapathy, Siva

AU - Popp, Juergen

N1 - Funding: Open Access funding enabled and organized by Projekt DEAL.

PY - 2025/7/10

Y1 - 2025/7/10

N2 - ABSTRACTBiophotonics—the interdisciplinary fusion of light‐based technologies with biology and medicine—is rapidly transforming research, diagnostics, and therapy across various domains. This white paper, developed in conjunction with the International Congress on Biophotonics 2024, offers a comprehensive overview of the current landscape and future potential of biophotonics. It discusses core technologies such as bioimaging, biosensing, and photonic‐based therapies, while highlighting novel applications in oncology, infectious diseases, neurology, cardiovascular health, agriculture, food safety, and environmental monitoring. The document also explores key enablers, including artificial intelligence, novel materials, and quantum biophotonics, along with critical challenges related to standardization, regulation, and clinical translation. A SWOT analysis and recommendations are provided to guide future research, commercialization, and interdisciplinary collaboration, underscoring biophotonics as a cornerstone of next‐generation precision medicine and the One Health approach.

AB - ABSTRACTBiophotonics—the interdisciplinary fusion of light‐based technologies with biology and medicine—is rapidly transforming research, diagnostics, and therapy across various domains. This white paper, developed in conjunction with the International Congress on Biophotonics 2024, offers a comprehensive overview of the current landscape and future potential of biophotonics. It discusses core technologies such as bioimaging, biosensing, and photonic‐based therapies, while highlighting novel applications in oncology, infectious diseases, neurology, cardiovascular health, agriculture, food safety, and environmental monitoring. The document also explores key enablers, including artificial intelligence, novel materials, and quantum biophotonics, along with critical challenges related to standardization, regulation, and clinical translation. A SWOT analysis and recommendations are provided to guide future research, commercialization, and interdisciplinary collaboration, underscoring biophotonics as a cornerstone of next‐generation precision medicine and the One Health approach.

KW - Artificial intelligence

KW - Bioimaging

KW - Biophotonics

KW - Biosensing

KW - Clinical translation

KW - Laser medicine

KW - One health

KW - Optical health technologies

KW - Photonic therapy

U2 - 10.1002/jbio.202500148

DO - 10.1002/jbio.202500148

M3 - Article

SN - 1864-063X

VL - 18

JO - Journal of Biophotonics

JF - Journal of Biophotonics

IS - 7

M1 - e202500148

ER -

Shining a light on the future of biophotonics

Abstract

UN SDGs

Keywords

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