Shigella shuts down the pyrop-technic show

Cristina Giogha; Jaclyn S. Pearson

doi:10.1016/j.chom.2021.09.012

Shigella shuts down the pyrop-technic show

Cristina Giogha, Jaclyn S. Pearson^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Shigella is a highly infectious human pathogen, yet mice are naturally resistant to infection. In this issue of Cell Host & Microbe, Luchetti et al. (2021) discuss this species specificity, demonstrating that Shigella directly targets the pore-forming protein Gasdermin D for degradation, thus preventing pyroptosis to enable infection of human cells.

Original language	English
Pages (from-to)	1473-1476
Number of pages	4
Journal	Cell Host and Microbe
Volume	29
Issue number	10
DOIs	https://doi.org/10.1016/j.chom.2021.09.012
Publication status	Published - 13 Oct 2021

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10.1016/j.chom.2021.09.012

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title = "Shigella shuts down the pyrop-technic show",

abstract = "Shigella is a highly infectious human pathogen, yet mice are naturally resistant to infection. In this issue of Cell Host & Microbe, Luchetti et al. (2021) discuss this species specificity, demonstrating that Shigella directly targets the pore-forming protein Gasdermin D for degradation, thus preventing pyroptosis to enable infection of human cells.",

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AB - Shigella is a highly infectious human pathogen, yet mice are naturally resistant to infection. In this issue of Cell Host & Microbe, Luchetti et al. (2021) discuss this species specificity, demonstrating that Shigella directly targets the pore-forming protein Gasdermin D for degradation, thus preventing pyroptosis to enable infection of human cells.

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Shigella shuts down the pyrop-technic show

Abstract

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