Sequence comparison between the haemagglutinin-neuraminidase genes of simian, canine and human isolates of simian virus 5

DU Baty, JA Southern, Richard Edward Randall

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7 Citations (Scopus)

Abstract

The nucleotide sequence of the haemagglutinin-neuraminidase (HN) gene was determined for a simian (W3), human (LN) and two canine (CPI+/CPI-) isolates of simian virus 5 (SV5). A comparison of the predicted amino acid sequences revealed that the human and canine isolates varied from the simian isolate by 1.7% and 2.4% respectively. This lack of significant variation between the HN proteins of the four SV5 isolates suggests that insufficient differences have occurred between isolates to confine them to a specific host.

Original languageEnglish
Pages (from-to)3103-7
Number of pages5
JournalJournal of General Virology
Volume72
Publication statusPublished - Dec 1991

Keywords

  • NEWCASTLE-DISEASE VIRUS
  • NUCLEOTIDE-SEQUENCE
  • MONOCLONAL-ANTIBODIES
  • MESSENGER-RNA
  • HN GENE
  • PARAMYXOVIRUS
  • PROTEIN
  • EVOLUTION
  • COMPLEX
  • TYPE-2

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