TY - JOUR
T1 - RP59500 (Quinupristin/dalfopristin)
T2 - Three case reports of its use in infection due to Enterococcus faecium
AU - Cassell, J.
AU - Balakrishnan, I.
AU - Samarasinghe, D.
AU - Mistry, P.
AU - Prentice, H. G.
AU - Gillespie, S. H.
PY - 1998/1/1
Y1 - 1998/1/1
N2 - We describe three cases of Entercoccus faecium sepsis arising in immunocompromised patients, severely ill with other conditions, who were treated with the new injectable streptogramin RP59500. There are still few reports of clinical experience with this drug. All had bacteriological resolution, with one patient recovering fully. Although two of the three patients died, this was due to underlying disease in one case and a Gram-negative superinfection in another. Quinupristin/dalfopristin therapy was not associated with significant adverse effects in any of the patients.
AB - We describe three cases of Entercoccus faecium sepsis arising in immunocompromised patients, severely ill with other conditions, who were treated with the new injectable streptogramin RP59500. There are still few reports of clinical experience with this drug. All had bacteriological resolution, with one patient recovering fully. Although two of the three patients died, this was due to underlying disease in one case and a Gram-negative superinfection in another. Quinupristin/dalfopristin therapy was not associated with significant adverse effects in any of the patients.
UR - http://www.scopus.com/inward/record.url?scp=0031864541&partnerID=8YFLogxK
U2 - 10.1016/S0163-4453(98)94495-4
DO - 10.1016/S0163-4453(98)94495-4
M3 - Article
C2 - 9661946
AN - SCOPUS:0031864541
SN - 0163-4453
VL - 36
SP - 324
EP - 327
JO - Journal of Infection
JF - Journal of Infection
IS - 3
ER -
