Role of pluripotent stem cells in regenerative medicine

Eriona Hysolli; Xiao Ling Zhou; Renjing Liu; Ji Hyun Kim; Brian Adams; Gareth Sullivan; In Hyun Park

doi:10.1201/b11937

Role of pluripotent stem cells in regenerative medicine

Eriona Hysolli, Xiao Ling Zhou, Renjing Liu, Ji Hyun Kim, Brian Adams, Gareth Sullivan, In Hyun Park^*

^*Corresponding author for this work

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Self-renewal and pluripotency place pluripotent stem cells in a unique position in the field of regenerative medicine. To date, a number of studies have demonstrated the improvement of damaged organ through the stem cell transplantation (Aboody et al. 2011, Wu and Hochedlinger 2011, Laflamme and Murry 2011, Melton 2011). There are various degenerative diseases that would benefit from cell therapy and thus potentially restoring damaged or lost tissue. The following section describes a number of degenerative diseases and trials using stem cell transplantation to potentially improve disease state. We will describe the current status of these therapies in preclinical animal models and/or clinical applications and the challenges facing their translation into the clinic.

Original language	English
Title of host publication	Regenerative Medicine, Stem Cells and the Liver
Publisher	CRC Press
Pages	21-37
Number of pages	17
ISBN (Electronic)	9781466513853
ISBN (Print)	9781578087396
DOIs	https://doi.org/10.1201/b11937
Publication status	Published - 1 Jan 2012

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AU - Sullivan, Gareth

AU - Park, In Hyun

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Role of pluripotent stem cells in regenerative medicine

Abstract

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