Rifampicin resistance in tuberculosis outbreak, London, England

C Jenkins, A P Claxton, R J Shorten, T D McHugh, S H Gillespie

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18 Citations (Scopus)

Abstract

Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance-determining region.

Original languageEnglish
Pages (from-to)931-934
Number of pages4
JournalEmerging Infectious Diseases
Volume11
Issue number6
Publication statusPublished - Jun 2005

Keywords

  • LINE PROBE ASSAY
  • MYCOBACTERIUM-TUBERCULOSIS
  • RPOB GENE
  • MUTATIONS

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