Rifampicin resistance in tuberculosis outbreak, London, England

C  Jenkins; A P  Claxton; R J  Shorten; T D  McHugh; S H  Gillespie

Rifampicin resistance in tuberculosis outbreak, London, England

C Jenkins, A P Claxton, R J Shorten, T D McHugh, S H Gillespie

Research output: Contribution to journal › Article › peer-review

Abstract

Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance-determining region.

Original language	English
Pages (from-to)	931-934
Number of pages	4
Journal	Emerging Infectious Diseases
Volume	11
Issue number	6
Publication status	Published - Jun 2005

Keywords

LINE PROBE ASSAY
MYCOBACTERIUM-TUBERCULOSIS
RPOB GENE
MUTATIONS

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Rifampicin resistance in tuberculosis outbreak, London, England",

abstract = "Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance-determining region.",

keywords = "LINE PROBE ASSAY, MYCOBACTERIUM-TUBERCULOSIS, RPOB GENE, MUTATIONS",

author = "C Jenkins and Claxton, {A P} and Shorten, {R J} and McHugh, {T D} and Gillespie, {S H}",

year = "2005",

month = jun,

language = "English",

volume = "11",

pages = "931--934",

journal = "Emerging Infectious Diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

number = "6",

}

TY - JOUR

T1 - Rifampicin resistance in tuberculosis outbreak, London, England

AU - Jenkins, C

AU - Claxton, A P

AU - Shorten, R J

AU - McHugh, T D

AU - Gillespie, S H

PY - 2005/6

Y1 - 2005/6

N2 - Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance-determining region.

AB - Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance-determining region.

KW - LINE PROBE ASSAY

KW - MYCOBACTERIUM-TUBERCULOSIS

KW - RPOB GENE

KW - MUTATIONS

UR - http://www.cdc.gov/ncidod/eid/vol11no06/04-1262.htm

M3 - Article

SN - 1080-6040

VL - 11

SP - 931

EP - 934

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 6

ER -

Rifampicin resistance in tuberculosis outbreak, London, England

Abstract

Keywords

UN SDGs

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