Rhodium/phospholane-phosphite catalysts give unusually high regioselectivity in the enantioselective hydroformylation of vinyl arenes

Gary M. Noonan; Christopher J. Cobley; Thomas Mahoney; Matthew L. Clarke

doi:10.1039/c3cc48823c

Rhodium/phospholane-phosphite catalysts give unusually high regioselectivity in the enantioselective hydroformylation of vinyl arenes

Gary M. Noonan, Christopher J. Cobley^*, Thomas Mahoney, Matthew L. Clarke

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Using the phospholane-phosphite ligand, BOBPHOS, almost perfect regioselectivities and high enantioselectivities (up to 92% ee) are observed in Rh catalysed enantioselective hydroformylation of vinyl arenes. This can be achieved under solvent-free conditions.

Original language	English
Pages (from-to)	1475-1477
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	12
Early online date	16 Dec 2013
DOIs	https://doi.org/10.1039/c3cc48823c
Publication status	Published - 11 Feb 2014

Keywords

Asymmetric Hydroformylation
Diazaphospholane LIGANDS
Heterocyclic olefins
Rhodium(I) complexes
RH(I)-(R,S)-Binaphos
Aldehydes
Alkenes

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10.1039/c3cc48823c

Clarke_2014_ChemComm_Rhodium_AM
© Royal Society of Chemistry 2014. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at http://dx.doi.org/10.1039/C3CC48823C
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Cite this

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abstract = "Using the phospholane-phosphite ligand, BOBPHOS, almost perfect regioselectivities and high enantioselectivities (up to 92\% ee) are observed in Rh catalysed enantioselective hydroformylation of vinyl arenes. This can be achieved under solvent-free conditions.",

keywords = "Asymmetric Hydroformylation, Diazaphospholane LIGANDS, Heterocyclic olefins, Rhodium(I) complexes, RH(I)-(R,S)-Binaphos, Aldehydes, Alkenes",

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AU - Noonan, Gary M.

AU - Cobley, Christopher J.

AU - Mahoney, Thomas

AU - Clarke, Matthew L.

PY - 2014/2/11

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N2 - Using the phospholane-phosphite ligand, BOBPHOS, almost perfect regioselectivities and high enantioselectivities (up to 92% ee) are observed in Rh catalysed enantioselective hydroformylation of vinyl arenes. This can be achieved under solvent-free conditions.

AB - Using the phospholane-phosphite ligand, BOBPHOS, almost perfect regioselectivities and high enantioselectivities (up to 92% ee) are observed in Rh catalysed enantioselective hydroformylation of vinyl arenes. This can be achieved under solvent-free conditions.

KW - Asymmetric Hydroformylation

KW - Diazaphospholane LIGANDS

KW - Heterocyclic olefins

KW - Rhodium(I) complexes

KW - RH(I)-(R,S)-Binaphos

KW - Aldehydes

KW - Alkenes

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DO - 10.1039/c3cc48823c

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VL - 50

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JO - Chemical Communications

JF - Chemical Communications

IS - 12

ER -

Rhodium/phospholane-phosphite catalysts give unusually high regioselectivity in the enantioselective hydroformylation of vinyl arenes

Abstract

Keywords

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Industry Fellowship 2012: Catalytic Enantioslective Alkene Carbonylation

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Rhodium/phospholane-phosphite catalysts give unusually high regioselectivity in the enantioselective hydroformylation of vinyl arenes

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Projects

Industry Fellowship 2012: Catalytic Enantioslective Alkene Carbonylation

Cite this