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Regulation of exosome release from mammary epithelial and breast cancer cells - a new regulatory pathway

Research output: Contribution to journalArticlepeer-review

Abstract

Exosomes are small 50-100nm sized extracellular vesicles released from normal and tumour cells and are a source of a new intercellular communication pathway. Tumour exosomes promote tumour growth and progression. What regulates the release and homoeostatic levels of exosomes, in cancer, in body fluids remains undefined.
Original languageEnglish
Pages (from-to)1025-34
Number of pages10
JournalEuropean Journal of Cancer
Volume50
Issue number5
Early online date24 Jan 2014
DOIs
Publication statusPublished - Mar 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Blotting, Western
  • Breast Neoplasms
  • Cell Line, Tumor
  • Cells, Cultured
  • Epithelial Cells
  • Exosomes
  • Extracellular Space
  • Female
  • Fluorescent Dyes
  • Humans
  • Mammary Glands, Human
  • Microscopy, Confocal
  • Organic Chemicals
  • Signal Transduction
  • Time Factors

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