Abstract
Exosomes are small 50-100nm sized extracellular vesicles released from normal and tumour cells and are a source of a new intercellular communication pathway. Tumour exosomes promote tumour growth and progression. What regulates the release and homoeostatic levels of exosomes, in cancer, in body fluids remains undefined.
Original language | English |
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Pages (from-to) | 1025-34 |
Number of pages | 10 |
Journal | European Journal of Cancer |
Volume | 50 |
Issue number | 5 |
Early online date | 24 Jan 2014 |
DOIs | |
Publication status | Published - Mar 2014 |
Keywords
- Blotting, Western
- Breast Neoplasms
- Cell Line, Tumor
- Cells, Cultured
- Epithelial Cells
- Exosomes
- Extracellular Space
- Female
- Fluorescent Dyes
- Humans
- Mammary Glands, Human
- Microscopy, Confocal
- Organic Chemicals
- Signal Transduction
- Time Factors