Regio- and stereoselective dimerization of terminal alkynes to enynes catalyzed by a palladium/imidazolium system

C L  Yang; Steven Patrick Nolan

doi:10.1021/jo010837s

Regio- and stereoselective dimerization of terminal alkynes to enynes catalyzed by a palladium/imidazolium system

C L Yang, Steven Patrick Nolan

Research output: Contribution to journal › Article › peer-review

Abstract

A Palladium/imidazolium chloride system has been used to mediate the dimerization of terminal alkynes to enynes. The combination of 1 mol % Pd(OAc)(2) and 2 mol % IMes.HCl in the presence Of CS2CO3 as base shows high activity and high regio- and steroselectivity for the dimerization of aryl and aliphatic terminal alkynes to enynes.

Original language	English
Pages (from-to)	591-593
Number of pages	3
Journal	The Journal of Organic Chemistry
Volume	67
Issue number	2
DOIs	https://doi.org/10.1021/jo010837s
Publication status	Published - 25 Jan 2002

Keywords

OLEFIN METATHESIS CATALYSTS
N-HETEROCYCLIC CARBENES
ARYL CHLORIDES
NUCLEOPHILIC CARBENES
METAL-COMPLEXES
RUTHENIUM
PALLADIUM
OLIGOMERIZATION
AMINATION
LIGANDS

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@article{b47d8a4a63fe46bb8c91cc55ad78be4b,

title = "Regio- and stereoselective dimerization of terminal alkynes to enynes catalyzed by a palladium/imidazolium system",

abstract = "A Palladium/imidazolium chloride system has been used to mediate the dimerization of terminal alkynes to enynes. The combination of 1 mol % Pd(OAc)(2) and 2 mol % IMes.HCl in the presence Of CS2CO3 as base shows high activity and high regio- and steroselectivity for the dimerization of aryl and aliphatic terminal alkynes to enynes.",

keywords = "OLEFIN METATHESIS CATALYSTS, N-HETEROCYCLIC CARBENES, ARYL CHLORIDES, NUCLEOPHILIC CARBENES, METAL-COMPLEXES, RUTHENIUM, PALLADIUM, OLIGOMERIZATION, AMINATION, LIGANDS",

author = "Yang, {C L} and Nolan, {Steven Patrick}",

year = "2002",

month = jan,

day = "25",

doi = "10.1021/jo010837s",

language = "English",

volume = "67",

pages = "591--593",

journal = "The Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society (ACS)",

number = "2",

}

TY - JOUR

T1 - Regio- and stereoselective dimerization of terminal alkynes to enynes catalyzed by a palladium/imidazolium system

AU - Yang, C L

AU - Nolan, Steven Patrick

PY - 2002/1/25

Y1 - 2002/1/25

N2 - A Palladium/imidazolium chloride system has been used to mediate the dimerization of terminal alkynes to enynes. The combination of 1 mol % Pd(OAc)(2) and 2 mol % IMes.HCl in the presence Of CS2CO3 as base shows high activity and high regio- and steroselectivity for the dimerization of aryl and aliphatic terminal alkynes to enynes.

AB - A Palladium/imidazolium chloride system has been used to mediate the dimerization of terminal alkynes to enynes. The combination of 1 mol % Pd(OAc)(2) and 2 mol % IMes.HCl in the presence Of CS2CO3 as base shows high activity and high regio- and steroselectivity for the dimerization of aryl and aliphatic terminal alkynes to enynes.

KW - OLEFIN METATHESIS CATALYSTS

KW - N-HETEROCYCLIC CARBENES

KW - ARYL CHLORIDES

KW - NUCLEOPHILIC CARBENES

KW - METAL-COMPLEXES

KW - RUTHENIUM

KW - PALLADIUM

KW - OLIGOMERIZATION

KW - AMINATION

KW - LIGANDS

U2 - 10.1021/jo010837s

DO - 10.1021/jo010837s

M3 - Article

SN - 0022-3263

VL - 67

SP - 591

EP - 593

JO - The Journal of Organic Chemistry

JF - The Journal of Organic Chemistry

IS - 2

ER -

Regio- and stereoselective dimerization of terminal alkynes to enynes catalyzed by a palladium/imidazolium system

Abstract

Keywords

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