TY - JOUR
T1 - Reductive Elimination at Carbon under Steric Control
AU - Tolentino, Daniel R.
AU - Neale, Samuel E.
AU - Isaac, Connie J.
AU - MacGregor, Stuart A.
AU - Whittlesey, Michael K.
AU - Jazzar, Rodolphe
AU - Bertrand, Guy
N1 - Publisher Copyright:
© 2019 American Chemical Society.
PY - 2019/6/26
Y1 - 2019/6/26
N2 - It has been previously demonstrated that stable singlet electrophilic carbenes can behave as metal surrogates in the activation of strong E-H bonds (E = H, B, N, Si, P), but it was believed that these activations only proceed through an irreversible activation barrier. Herein we show that, as is the case with transition metals, the steric environment can be used to promote reductive elimination at carbon centers.
AB - It has been previously demonstrated that stable singlet electrophilic carbenes can behave as metal surrogates in the activation of strong E-H bonds (E = H, B, N, Si, P), but it was believed that these activations only proceed through an irreversible activation barrier. Herein we show that, as is the case with transition metals, the steric environment can be used to promote reductive elimination at carbon centers.
UR - http://www.scopus.com/inward/record.url?scp=85067952150&partnerID=8YFLogxK
U2 - 10.1021/jacs.9b04957
DO - 10.1021/jacs.9b04957
M3 - Article
C2 - 31180660
AN - SCOPUS:85067952150
SN - 0002-7863
VL - 141
SP - 9823
EP - 9826
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 25
ER -